Romantic gestures that men make toward the women they love or whose heart they wish to win often involve providing help—whether it is opening and holding the door, paying for her drink, lifting her heavy suitcase, or completing a complicated task. In these everyday interactions, helping relations between men and women are rarely explicitly framed as intergroup helping, but rather as interperson...

this article aims, with a detailed insight into the historical process of khul’ divorce in two phases in arabia before islam and after islam, to discover the creation of successive theories and the evolution of ‘the khul’ divorce institution’ to its current form as supporting iranian legislation. while presenting the views of the jurists, we encountered two streams of thought as regards the dis...

466 | CANCER DISCOVERY MAY 2016 www.aacrjournals.org An international team of researchers— led by Susan Halabi, PhD, a professor of biostatistics at Duke University School of Medicine in Durham, NC—gathered information from nine phase III studies, encompassing 8,736 men with mCRPC. The patients in these trials had all received docetaxel as standard therapy. The researchers classifi ed them into...

132 Background: We report results of a phase I/II clinical trial of BPX-101, a drug- activated autologous DC vaccine targeting PSMA. METHODS Men with progressive mCRPC following up to one prior chemotherapy regimen were enrolled in a 3+3 dose escalation trial evaluating BPX-101 and CD40 activating agent AP1903. BPX-101 was administered intradermally every 2 weeks for 6 doses, during the induc...

Rapid molecular evolution in retroviruses potentially pose a hurdle to effective vaccine design. While the coding sequence for viral surface proteins seemingly mutate randomly from point to point, the necessity of conserved function dictates the often suspected existence of hidden correlations and longrange dependencies between non-colocated sequence positions. In this initial report, we presen...

Dear Editor, We describe a 25-year-old man who presented with a 6-month history of persistent, daily, severe, retro-orbital and left-sided hemicranial headache that was associated with persistent numbness of the left forehead and decreased pinprick sensation over that region. He exhibited partial left-third nerve palsy expressed as partial ptosis of the left eye, weakness of the left inferior o...

Background: Psoriatic arthritis (PsA) is a chronic inflammatory condition associated with psoriasis. The common clinical features of PsA include peripheral arthritis, dactylitis, enthesitis, spondylitis, skin and nail disease 1 . Considering the heterogeneous course different patient characteristics, there need to standardize management patients. At present, no established guidelines are availa...

Michael A. Thompson, MD, PhD; Jeffrey P. Henderson, Pankil K. Shah, MSPH; Samuel M. Rubinstein, MD; J. Joyner, Toni Choueiri, Daniel B. Flora, PharmD; Elizabeth Griffiths, Anthony Gulati, Clara Hwang, Vadim S. Koshkin, Esperanza Papadopoulos, V. Robilotti, MPH; Christopher T. Su, Wulff-Burchfield, Zhuoer Xie, MS; Peter Paul Yu, Sanjay Mishra, MS, Jonathon W. Senefeld, Dimpy Jeremy L. Warner, CO...

Background: Intravenous vitamin C (IVC) may have anti-cancer and anti-inflammatory properties. Many studies have demonstrated that IVC has a good safety profile, and can improve the quality of life of cancer patients. IVC has been proposed as an adjuvant treatment for cancer in conjunction with other therapies. Design: A retrospective study was conducted using clinical data from the Riordan Cli...