BACKGROUND AND OBJECTIVE Haemophilus influenzae type b (Hib) is divided into two distinct genotypes, type I and type II, based on the structure of capsular polysaccharides. The capsulation locus of Haemophilus influenzae type b consists of three functionally distinct regions, designated regions 1 to 3. Region III contains hcsA and hcsB genes; however, notable sequence variation in this region c...

Effect of vaccination with Haemophilus influenzac type b (Hib) conjugate vaccine ott the oropharyngeal carriage of Hib. In: Programs and abstracts of the -30th inieyscience conference on antimicrobial agents and chemotherapy. Atlanta, Georgia: American Society for Microbiology, 1990: 187. (Abstract 605.) 24 Ward JI, Fraser DlW, Baraft' LJ, Plikaytis Bi). Haemophilus influenzae meningitis. A nat...

had not been given to contacts of these patients, but only one of the "secondary" cases occurred within 30 days of the index case; the others were two months and three months apart. Although rifampicin prophylaxis is of limited value, the relatively poor compliance with the current recommendations suggests that its value is commonly reduced even further by incorrect use. There has been concern ...

Community-acquired pneumonia is a common disease and a frequent cause of morbidity and mortality worldwide. Haemophilus influenzae is a leading cause of CAP. The current study was conducted to determine the serotype distribution and antimicrobial susceptibility patterns of Haemophilus influenzae isolated from unvaccinated adult patients with CAP at Assiut University Hospitals. Materials and Met...

The age-related acquisition of serum anticapsular and bactericidal antibodies to Haemophilus influenzae type b observed in rats was similar to that of humans. The antigenic source for this "natural" immunity was not identified, since neither pharyngeal infection with H. influenzae b nor enteric colonization by cross-reacting bacteria was detected. Infant rats surviving H. influenzae b bacteremi...

Thirteen patients with Haemophilus influenzae type b pneumonia are reported to emphasise the clinical, radiographic, and therapeutic aspects of this illness. All but one patient was under 2 1/2 years of age. The presenting complaint was a variable duration of upper respiratory infection and fever in most cases. One-third of patients had radiographic evidence of pleural involvement; one-third sh...

Before the introduction of effective vaccines, H. influenzae, type b (Hib) was the leading cause of bacterial meningitis and other invasive bacterial disease among children less than 5 years of age. In 1997, ten confirmed cases of invasive disease caused by the serotype b strain of H. influenzae were reported. This is the first year that the number of cases increased since the conjugate vaccine...

In the period November 1967 to September 1968 Haemophilus influenzae type b was isolated from the blood of 11 young children. Only three of these presented with meningitis; others had septic arthritis, oesteomyelitis, subcutaneous abscesses, cellulitis, respiratory infections, and undifferentiated pyrexia. During the preceding five years H. influenzae type b was isolated from the blood cultures...