Since in-feed antibiotics (IFAs) are being taken out of broiler diets around the world, beginning in Sweden in the year 1986, the search for alternatives to replace IFAs has gained increasing interest in animal nutrition. Gut microflora appears to be the target for IFAs and alternatives to exert health benefits and some growth-promoting effects. In this review the effect of six kinds of alterna...

Effective antimicrobial stewardship requires a better understanding of the impact different antibiotics on gut microflora. Studies with humans are confounded by large interindividual variability and difficulty in identifying control cohorts.

In humans, microbial colonisation of the intestine begins just after birth. However, development of the normal flora is a gradual process, which is initially determined by factors such as genetic aspects, the maternal-foetal interaction, place and mode of delivery, early feedings strategies, and the use of antibiotics. Current knowledge on the significance and impact of the gut microflora on th...

Antibiotic-treated and untreated Syrian hamsters were inoculated intragastrically with Candida albicans to determine whether C. albicans could opportunistically colonize the gastrointestinal tract and disseminate to visceral organs. Antibiotic treatment decreased the total population levels of the indigenous bacterial flora and predisposed hamsters to gastrointestinal overgrowth and subsequent ...

OBJECTIVE Recent work indicates that the gut microflora is altered in patients with coeliac disease (CD). Faecal short-chain fatty acids (SCFAs) are produced by the gut microflora. We have previously reported a high SCFA output in children with symptomatic and asymptomatic CD at presentation, as well as in CD children on a gluten-free diet (GFD) for less than 1 year, indicating deviant gut micr...

The gastrointestinal (GI) tract represents a complex ecosystem in which a balance exists between the intestinal microflora and the host. The microflora comprises predominantly of facultative anaerobes e.g. lactobacillus and obligate anaerobes e.g. bifidobacterium. Aerobic organisms are not present in the GI tract of healthy individuals except Pseudomonas in very small numbers. Most of the gut m...

conclusions the results showed that although the human gut microbiome plays a pivotal role in health in a normal concentration, fluctuation in their number (increase or decrease) is a possible factor in the appearance of major diseases. context the composition and function of the gut microbiota develop with their host from birth. the human microbiome, especially the gut microbiota, plays a crit...

During the last decade, the important role of gut microflora as a special organ of the gastrointestinal system in the metabolism of drugs is well known. The aim of this study was to evaluate the role of the gut microecological population with enzymatic systems, especially beta-lyase, in the metabolism of paracetamol in mice. Two groups of 20 white male laboratory mice BALB/c, body weight 32+/-1...

The microbiota of the human gastrointestinal tract plays a key role in efficient nutrient absorption and thus maintaining human health. Through the process of fermentation, gut bacteria metabolize various nutritional substrates to end products such as organic acids, vitamins, short-chain fatty acids etc. Therefore, an optimum balance is required between the intestinal microflora and its host. U...