Monoclonal antibodies (Mabs) were produced against the early Polish strains of infectious bursal disease virus (IBDV) isolated from subclinical cases of Gumboro disease between 1978 and 1980. Splenocytes from immunized mice were fused to myeloma cells and hybridomas producing antibodies against homologous and different pathotype of IBDVs were selected by indirect ELISA, immunoperoxidase, ELISA-...

Introduction Infectious bursal disease (IBD) is an acute contagious viral disease of young chickens known as Gumboro disease (Lasher and Shane, 1994). The etiological agent, IBD virus (IBDV), has a predilection for the cells of the bursa of Fabricius where the virus infects lymphocytes of the B-cell lineage (Burkhardt et al., 1987). Thus, IBD is a fatal immunosuppressive disease causing heavy l...

Infectious bursal disease virus (IBDV) belongs to the family Birnaviridae and is economically important to the poultry industry worldwide. IBDV infects B cells in the bursa of Fabricius (BF), causing immunosuppression and morbidity in young chickens. In addition to strains that cause classical Gumboro disease, the so-called 'very virulent' (vv) strain, also in circulation, causes more severe di...

Vaccination in poultry production is vital to protect the birds against the main viral diseases: Marek’s disease, infectious bursal disease or Gumboro disease, infectious bronchitis, Newcastle disease, avian influenza, etc, as well as bacterial diseases: colibacillosis, mycoplasma infections, etc and also coccidiosis. If we refer more specifically to broiler chicken meat production worldwide, t...