Nine new species of the family Nesticidae, collected from caves in Guangxi, Guizhou, Henan and Yunnan Provinces of China, are diagnosed, described and illustrated: Nesticella apiculata n. sp., Nesticella arcuata n. sp., Nesticella falcata n. sp., Nesticella gracilenta n. sp., Nesticella semicircularis n. sp., Nesticella shanlinensis n. sp., Nesticella verticalis n. sp., Nesticus globosus n. sp....

CYP3A29 is the most important key enzyme for drug metabolism in pig's liver. Research of the characters of CYP3A29 mRNA expression in Chinese experimental miniature pig's livers is significant for evaluating it whether suitable for experimental model for drug metabolism mediated by human CYP3A4 enzyme. In this study, the levels of CYP3A29 mRNA expression in livers of Bama miniature pigs, Guizho...

OBJECTIVE The aim of the study was to establish the contemporary epidemiological characteristics of Japanese encephalitis (JE) in Guizhou Province. METHODS A retrospective study of National Notifiable Disease Reporting System (NNDRS) data from 1971 through 2009, was conducted to ascertain the geographical, seasonal, and age distributions of JE incidence in Guizhou Province, China. RESULTS A...

The dengue viruses (DEN, genus Flavivirus, family Flaviviridae) are mosquito borne and have caused 100 million cases of dengue fever each year in most tropical and subtropical areas of the world. However, in the southwest area of Yunnan-Guizhou Plateau, China, the previous work demonstrated that different geographic strains of Aedes albopictus were susceptible to dengue virus. In this study, we...

The present study was aimed to analyze the frequencies of human leukocyte antigen (HLA)-A, -B, and -DRB1 alleles and A-B-DRB1, A-B, A-DRB1 and B-DRB1 haplotypes in inhabitants of Guizhou province, China. All samples were typed in the HLA-A,-B, and -DRB1 loci using the polymerase chain reaction-reverse sequence specific oligonucleotide probe (PCR-rSSOP) method and HLA polymorphisms were analyzed...

In this study, we report the complete genome sequence of a novel Newcastle disease virus (NDV) strain, Sheldrake duck/China/Guizhou/SS1/2014, isolated from Sansui Sheldrake duck flocks in Guizhou Province, southwestern China. The genome of this isolate is 15,192 nucleotides in length, which belongs to NDV genotype VIId in class II. This discovery will help us further study the epidemiology char...

Development of CXCR4 antagonist for treatment of AIDS Wan-Gang Gu1* and Xuan Zhang2 1Department of Immunology, Zunyi Medical University, Zunyi, Guizhou, 563000, China 2School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming Yunnan 650500, China *Corresponding author: Dr. Wan-Gang Gu, Department of Immunology, Zunyi Medic...

Mercury (Hg) is a global pollutant and poses a worldwide concern due to its high toxicity. Guizhou province is recognized as a heavily Hg-polluted area in China due to both the special geochemical background and human activities. Here an integrated overview of current knowledge on the behavior of Hg in environments, as well as human health risk with respect to Hg contaminations in Guizhou was p...

one grotesque catfish specimen was collected in zhangjiang river (upper reach of a secondary tributary of hongshuihe river) in libo county, guizhou province, china. this specimen bears surprising character of four dorsal fins, which have not appeared in any other silurid fishes. but other morphological characters, such as two pairs of barbels, lower jaw projecting beyond upper jaw, the first do...

OBJECTIVE To identify and type three leptospires isolated from Rattus tanezumi in Guizhou Province by using three molecular techniques (PFGE, MLVA, and MLST), reveal the molecular characteristic of causative agents of local leptospirosis and evaluate these three molecular methods based on their detection resolution and efficiency. METHODS Three Leptospira strains were isolated from the kidney...