background: asthma is a chronic inflammatory disorder of the airways. the available treatment options have major limitations owing to low efficacy, associated adverse events and compliance issues. therefore, the health burden of bronchial asthma is increasing globally at an alarming rate, providing a strong impetus for the development of new therapeutics. myrica sapida is known traditionally in...

Foot-and-mouth disease (FMD) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. This study quantifies the cytokines mRNA expression of vaccinated guinea pigs withFMD type O inactivated vaccine. Blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. Extracted mRNAs were reverse-transcribed into cDNA and analyz...

Introduction: To describe the underlay tympanoplasty technique using an acellular dermal graft(AlloDerm) for tympanic membrane (TM) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using AlloDerm tissue harvested from the prepuce as a source of tissue for future grafting in human TM reconstruction.   Materials and Methods: The prepuce was divided during c...

objective: the effects of natural adjuvants were examined on total and differential wbc counts in lung lavage of sensitized guinea pigs. materials and methods: in three sensitized groups of guinea pigs including: untreated sensitized animals (s), sensitized animals treated with adjuvant g2 (s+g2) and g2f (s+g2f) as well as non-sensitized group (c) (n=6 for each group), total and differential wb...

There is documented evidence that infection in laboratory animals can often influence the outcome of experiments. All infections, apparent or inapparent, are likely to increase biological variability. As a research project concerning the diversity and distribution of parasites of rabbit and guinea pig in a conventional laboratory animal house, about 87 rabbits (from 700 ) and 105 guinea pigs (f...

introduction: to describe the underlay tympanoplasty technique using an acellular dermal graft(alloderm) for tympanic membrane (tm) reconstruction in a guinea pig model and to demonstrate the feasibility of the technique using alloderm tissue harvested from the prepuce as a source of tissue for future grafting in human tm reconstruction.   materials and methods: the prepuce was divided during c...

objective(s): the effect of the extract of crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   materials and methods: ovalbumin (oa) sensitized guinea pigs were given drinking water alone (group s), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6...

the current study intends to analyze the effects of methionine on the ovulation of guinea pigs. 60 guinea pigs were given 4 different treatments in a completely randomize design. the treatments contained 0, 2, 4 and 6 percent of methionine per kg as fed. after two weeks as adaptation period, the four different treatments were given to the animals for two estrus cycle. after synchronization whic...

chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and g banding techniques. the chromosomes diploid number was 2n= 64 and polymorphism of three type chro...