participation in clinical trials can be useful for the health of a person, in who it is conducted, but it does not have to be - it can even be harmful. therefore, primary motive to accept such risk is humanity and human wish to contribute to the progress of medicine; this is expressed by personal consent. the consent, however, can be an expression of personal humanity, and for this, it is not l...

Nearly 50 % of newly diagnosed colorectal cancer, affect people over 70 years of age. Inclusion of older patients in clinical trials has been extremely rare. As a result, there is debate on how to manage these patients because it is still unclear how to balance the therapeutic advantages and toxicities. For patients who do not have comorbid conditions, with performance status (P.S.) 0–1, treatm...

Overview Fueled by the aging global population and economic growth of developing countries, the demand for new, safe, and effective therapeutics for neurological conditions in the US and globally will increase dramatically over the next generation. Scientific discovery and clinical investigation are critical for developing and evaluating new treatments and can have substantial public health ben...

conclusions there is not enough evidence to support or refute the routine use of fish oil supplements during pregnancy for the prevention or treatment of diabetes. it is suggested that further randomized controlled trials be conducted to evaluate the role of fish oil supplementation in pregnancy. context one of the most common complications of pregnancy is gestational diabetes mellitus (gdm), w...

stroke is an important cause of death in the world and disability world‑wide especially in developed countries. following acute phase of stroke, some procedures and medical treatment such as thrombolytic agents has been recommended; nevertheless many patients have enduring deficits. thus, there is a realistic need to develop treatment strategies for reducing neurological deficits. however, the ...

BACKGROUND Nowadays, a large number of students experience spinal pain quite early in life due to heavy school bag loads. Moreover, external forces in the form of school bags may influence the normal growth, development of children and adolescents, and also maintenance of alignment of their bodies, which can pose a huge threat to postural integrity under external load. Awareness about the appro...

Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...

the use of more competitive species and cultivars in small grain cereal production may help to develop production systems that require less herbicide. this study was designed to identify root and shoot characteristics of cereal seedlings that would allow distinguishing the more competitive (mc) cultivars from the less competitive (lc) ones. two growth cabinet trials were conducted using four cr...

this research was conducted to study the performance of barley green fodder (bgf) yield in hydroponic system fed to fattening lambs. in a 16 week experiment, barley grain was grown in hydroponic system, during 5 and 7 days growing periods and the green fodder was included in the diet of fattening lambs, within two different feeding trials. the first trial was aimed to compare the bgf with barle...