AIM Orbital granulocytic sarcoma is a localised tumour composed of cells of myeloid origin. Histological diagnosis can be difficult in patients with poorly differentiated orbital tumours and no evidence of systemic leukaemia. The naphthol AS-D chloracetate esterase (Leder stain) and immunohistochemical stains for lysozyme and MAC387 were used to determine the staining characteristics of these t...

Granulocytic sarcoma is a rare extramedullary tumor composed of myeloid progenitor cells. Primary involvement of the biliary tract without evidence of leukemia is exceedingly rare. Here, we report an isolated biliary granulocytic sarcoma in a 30-yr-old man who presented with jaundice, fever, and chill without any evidence of leukemia. However, five months after the diagnosis, he developed acute...

Granulocytic sarcoma is an extramedullary tumor which is composed of myeloblasts and immature myeloid cells. It usually occurs in association with acute myeloid leukemia and most commonly involves skin, soft tissue, lymph nodes, bone, and periosteum. We report a case of isolated ureteral granulocytic sarcoma without hematologic manifestations. Our patient presented with bloody urine and left-si...

Intracranial granulocytic sarcoma was a relatively rare tumor composed of myeloid blasts and/or immature myeloid cells in an extramedullary site which is associated with acute/chronic myeloid leukemia. In this paper, two cases of intracranial granulocytic sarcoma, one male aged 36 and one 28-year-old female, were reported to improve the diagnosis and treatment of such diseases. Diagnostic and t...

Granulocytic sarcoma is a rare disease that is rarely curable with conventional chemotherapy. This report describes a case of a patient with bulky granulocytic sarcoma of the retroperitoneum who was treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation without administering granulocyte colony-stimulating factor before stem cell collection. According to bo...

Refractory anemia with ring sideroblasts associated with marked thrombocytosis (RARS-T) and granulocytic sarcoma are two rare myeloid neoplasms. RARS-T is a Myelodysplastic/Myeloproliferative Neoplasm (MDS/MPN) characterized by overlapping myeloproliferative (platelets count higher than 450x109/L associated with proliferation of large atypical megakaryocytes similar than those observed in essen...

Granulocytic sarcoma is a form of extramedullary leukaemia. The intraparenchymal localisation is extremely rare. We report a case of cerebellar granulocytic sarcoma occuring in a 43 years old woman without any precedent medical history. The diagnosis of granulocytic sarcoma was established by neoplastic cells findings through morphological and immunohistochemical studies. The patient died few d...

Objective: We report an extremely rare case of granulocytic sarcoma in bilateral temporal bones. Methodology: Case report and a review of related literature. Results: The patient was initially performed neoplasm ectomy then systemic chemotherapy in his left ears. After surgery the patient got a significant improvement of his left hearing. One year later systemic chemotherapy was established aga...

Granulocytic sarcoma (in the past sometimes called chloroma because of the grossly greenish tinge of the tumoral tissue due to the presence of the enzyme myeloperoxidase) is a dramatic manifestation of acute myelogenous or myelomonocytic leukemia. A soft-tissue or an organ mass created by leukemic cells dominates the clinical presentation or develops later in the course of the disease after an ...