The Alzheimer’s disease (AD) is a progressive and degenerative disease of the brain which causes a serious impairment over its two main activities: thinking and memory. According to Celsis (Celsis, 2000), AD is the most common form of dementia among the elderly population, comprising up to 75% of all dementia cases. AD causes a gradual loss of intellectual abilities with deterioration in cognit...

A 44-year-old woman presented at the Western Eye Hospital, London, with a 3-month history of gradual, painless, bilateral deterioration of her vision. She had no other ocular symptoms and no previous ocular history. Review of systems was unrevealing, and her medical history was unremarkable: she did not complain of headaches or anosmia, nor was she taking any regular medication. She was of norm...

We read with interest the observational study by Paula Ramirez et al. [1] discovering the appropriate starting time of antibiotic treatment in patients with ventilatorassociated pneumonia (VAP). In that study, 440 patients receiving mechanical ventilation were screened, but only patients with VAP were studied, including 43 with gradual VAP and 28 with non-gradual VAP, and they suggested that ea...

OBJECTIVE To elucidate the relationship between the subjective assessment in patients with glaucoma of (1) the severity of their visual loss, and (2) any deterioration in their visual function and their objective visual fields as measured by computed perimetry. DESIGN First, patients completed a questionnaire relating to perceived visual disability and underwent binocular visual field testing...

Session types enable fine-grained static control over communication protocols. Gradual typing is a means to safely integrate statically and dynamically typed program fragments. We propose a calculus for synchronous functional two-party session types, augment this calculus with a dynamically typed fragment as well as coercion operations between statically and dynamically typed parts, and establi...

PURPOSE To report the time course of changes in corneal wavefront aberrations in a patient with pellucid marginal degeneration. CASE A 59-year-old man with pellucid marginal degeneration was followed-up annually with slit-lamp microscopy and videokeratography for 11 years. The anterior corneal height data of the videokeratography were expanded into the set of orthogonal Zernike polynomials to...

OBJECTIVES To describe prospectively the long-term changes of quality of life and mood in patients with squamous cell carcinoma of the head and neck treated with surgery and/or radiotherapy. PATIENTS AND METHODS One hundred seven patients completed the European Organization for Research and Treatment of Cancer (EORTC) Core Questionnaire, the EORTC Head and Neck Cancer Module, and the Center f...

The linings of tunnels in cold regions with long service lives usually have cracks, parts the structure peeling and falling off, which seriously threatens tunnel safety operation. unsaturated freeze–thaw cycle concrete, is main cause structural deterioration, has not received much research attention. During life regions, cycles deteriorate quality its degree presents a gradual distribution circ...

the term ‘deteriorated texture’ gives all experts as well as ordinary people almost the sameimpression. despite common points in images, the differences put iran cities in different categories based on deteriorated textures. this classification not only has negative effect on the audience from mental point of view but causes various problems for the experts in determining interference method. f...