نتایج جستجو برای: gra7

تعداد نتایج: 55  

ژورنال: :پژوهش های آسیب شناسی زیستی 0
fatemeh ghaffarifar associated professor, department of parasitology, school of medical sciences, tarbiat modares university, tehran, iran rahme nordin professor, research center of molecular medicine, usm university, penang, malaysia zohreh sharifi assistant professor, research center of virology, iranian blood transfusion organization, tehran, iran abdolhossein dalimi professor, department of parasitology, school of medical sciences, tarbiat modares university, tehran, iran shahla roudbar mohammadi assistant professor, department of mycology, school of medical sciences, tarbiat modares university, tehran, iran sakineh ghasemi nikoo m.sc., department of parasitology, school of medical sciences, tarbiat modares university, tehran, iran

هدف: توکسوپلاسما گونده ای تک یاخته ای داخل سلولی و عامل ایجاد توکسوپلاسموزیس بوده و دارای انتشار جهانی است. در سال های اخیر پیشرفت هایی در زمینه تهیه واکسن صورت گرفته که منجر به ایجاد پاسخ های محافظت کننده شده است. آنتی ژن gra7 با وزن مولکولی 29 کیلودالتون یک آنتی ژن ترشحی گرانولی فشرده است که به وسیله سلول های آلوده میزبان آزاد می شود. در سلول های آلوده به تاکی زوئیت، پروتئین 29 کیلو دالتونی د...

Journal: :International journal for parasitology 2010
N Parameswaran R C A Thompson N Sundar S Pan M Johnson N C Smith M E Grigg

Australia is geographically isolated and possesses a remarkable diversity of wildlife species. Marsupials are highly susceptible to infection with the cosmopolitan parasite Toxoplasma gondii. Of 46 marsupials screened for T. gondii by multilocus PCR-DNA sequencing at polymorphic genes (B1, SAG3, GRA6, GRA7), 12 were PCR-positive; the majority (67%; 9/12) were infected by non-archetypal Type II-...

Journal: :Infection and immunity 2000
M Vercammen T Scorza K Huygen J De Braekeleer R Diet D Jacobs E Saman H Verschueren

C57BL/6, C3H, and BALB/c mice were vaccinated with plasmids encoding Toxoplasma gondii antigens GRA1, GRA7, and ROP2, previously described as strong inducers of immunity. Seroconversion for the relevant antigen was obtained in the majority of the animals. T. gondii lysate stimulated specific T-cell proliferation and secretion of gamma interferon (IFN-gamma) in spleen cell cultures from vaccinat...

Journal: :Experimental parasitology 2010
Veronica M Cóceres Melina Laguia Becher Maximiliano G De Napoli María M Corvi Marina Clemente Sergio O Angel

Recombinant Toxoplasma gondii small heat shock protein HSP20, surface antigen SAG1 and dense granule GRA7 were analyzed by IgG-ELISA with serum samples of Toxoplasma infected humans grouped as I (IgG+, IgM+), II (IgG+, IgM-) and III (IgG-, IgM-). rHSP20 reacted against 80% and 62.5% of serum samples from groups I and II, respectively. rSAG1 was recognized by 85% of the samples from group I and ...

Journal: :Cell 2006
Isabelle Coppens Joe Dan Dunn Julia D. Romano Marc Pypaert Hui Zhang John C. Boothroyd Keith A. Joiner

The intracellular compartment harboring Toxoplasma gondii satisfies the parasite's nutritional needs for rapid growth in mammalian cells. We demonstrate that the parasitophorous vacuole (PV) of T. gondii accumulates material coming from the host mammalian cell via the exploitation of the host endo-lysosomal system. The parasite actively recruits host microtubules, resulting in selective attract...

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