an efficient method for the friedel–crafts acylation of a wide range of aromatic compounds in good to excellent yields under solvent-free conditions, using iron zirconium phosphate (zpfe) was investigated. the catalyst is easy to prepare and shows interesting catalytic properties. the catalyst was characterized by some instrumental techniques such as xrd, icp-oes, sem and tem. a wide variety of...

A variety of alcohols readily add to 3,4-dihydro-2H-pyran under solvent free conditions in the presence of catalytic amount of acidic ionic liquid [Et3N(CH2)4SO3H][OTs] to afford the corresponding tetrahydropyranyl ethers in good to excellent yields at room temperature. The use of this procedure allows easy separation of the desired products ...

A rapid and efficient one-pot, four-component protocol towards the synthesis of polyhydroquinoline derivatives has been developed. The condensation of aldehyde, dimedone, ethyl acetoacetate and ammonium acetate in presence of stannous chloride was carried out under solvent free condition to synthesize a variety of polyhydroquinoline derivatives in good to excellent yields. Stannous chloride was...

A variety of alcohols readily add to 3,4-dihydro-2H-pyran under solvent free conditions in the presence of catalytic amount of acidic ionic liquid [Et3N(CH2)4SO3H][OTs] to afford the corresponding tetrahydropyranyl ethers in good to excellent yields at room temperature. The use of this procedure allows easy separation of the desired products ...

treatment of 10-bromoanthralin (1) with several thiophenols (2) gave the corresponding 10-arylthioanthralins (3) in high yields. oxidation of thioanthralins (3a-c) and (3k-m) using an excess of m-chloroperbenzoic acid gave the corresponding sulfones (4a-c) and (4k-m) in good yields. oxidation of thioanthralins (3d-f) gave a mixture of the corresponding sulfones (4d-f) and anthralin-10,10'-dehyd...

one pot solvent less synthesis of amidoalkylnaphthol derivatives via reaction of aldehydes, 2-naphthol and acetamide/urea in the presence of phenylphosphinic acid is  described. this methodology provides a simple synthetic route to amidoalkylnaphthols in good to high yields.

5-Substituted-1H-tetrazoles were synthesized by the [3 + 2] cycloaddition of sodium azide with various nitriles in the presence of nickel zirconium phosphate (NiZrP) as an effective heterogeneous catalyst in dimethylsulfoxide at 120 °C. This method has the advantages of good to high yields, simple methodology and easy work-up. The catalyst can be recovered by centrifuging and reused with good y...

This work described an efficient Pseudo four-component synthesis of (10E)-N-benzylidene-2-phenylH-imidazo[1,2-a]pyridin-3-amine derivatives from 2-aminopyridin, malononitrile and arylaldehydes in the presence of NaOH under solvent-free and conventional heating condition in good to excellent yields. A wide range of aromatic aldehydes would easily undergo condensations with 2-aminopyridin and mal...