نتایج جستجو برای: gonadotoxicity
تعداد نتایج: 77 فیلتر نتایج به سال:
background: doxorubicin (dox), an anthracycline antibiotic, is a widely used anticancer agent. in spite of its high antitumor efficacy, the use of dox in clinical chemotherapy is limited due to diverse toxicities, including gonadotoxicity. objective: we investigated the protective effect of nano-zinc oxide (nzno) as an established antioxidant on dox-induced testicular disorders. materials and ...
To reduce chemotherapy induced gonadotoxicity, co-treatment with gonadotropin releasing hormone against analogue (GnRHa) was tested using rat model. Leuprorelin acetate (Leuplin) with or without cisplatin (CDDP) was given subcutaneously at a dose of 9.4 microg/ml to Wistar strain female rats. The total number of follicles was counted and the maturation of follicles was evaluated at the largest ...
Twenty-one Wistar rats weighing 200 - 250 mg were categorized into three treatment groups- the control, saline and cisplatin groups, each comprising of seven per group, to assess effects cisplatin-induced testicular damage in rats. The control group received feed mash water ad libitum, equal volumes physiological intraperitoneally with normal feeds water, while cisplastin 8 mg/kg body weight on...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید