This paper describes a microparticle delivery device that generates a plasma jet through laser ablation of a thin metal foil and uses the jet to accomplish particle delivery into soft living targets for transferring biological agents. Pure gold microparticles of 1 µm size were coated with a plasmid DNA, pIG121Hm, and were deposited as a thin layer on one surface of an aluminum foil. The laser (...

To establish Boron Neutron Capture Therapy (BNCT) for non-resectable liver metastases and for in vitro experiments at the TRIGA Mark II reactor at the University of Mainz, Germany, it is necessary to have a reliable dose monitoring system. The in vitro experiments are used to determine the relative biological effectiveness (RBE) of liver and cancer cells in our mixed neutron and gamma field. We...

In the beginning of the 20th century, physicists had begun to determine the structure of atoms. J.J. Thomson had discovered the presence of electrons negatively charged particles with a mass much less than the overall mass of the electron using cathode rays[1]. Thomson further hypothesized that the full structure of the atom consisted of electrons surrounded by a ”soup” of positive charge. This...

A gold foil ERG electrode is described. The device is inexpensive and simple to fabricate. Since it is hooked over the lower lid and makes minimal touch contact with the inferior limbal area, it can be used in circumstances which require prolonged testing of retinal function or in eyes with corneal pathology. Because the optics of the eye are not compromised, it is possible, with the use of app...

Thin-film gold electrodes were produced by radio-frequency sputtering using a polyvinyl chloride foil as substrate. The voltammetric behavior was characterized in various electrolyte solutions. In alkaline and neutral aqueous solutions reliable voltammetric measurements can be performed while in acidic media some nondefined phenomena occur. A novel type of electrode for batch injection analysis...

Qualitative defects and resistances in 94 used gold foil electrodes were examined. The electrodes were divided into four groups of varying resistances and gold coating defects. Ten were randomly selected from each group to measure standard photopic electroretinograms (ERGs) in a normal subject. Ten new electrodes were used as controls. There was no significant difference among the electrode gro...

The plasma physics group at GSI investigates among other issues the energy loss of heavy ions in laser produced plasma [1]. The current experimental setup consists of an ion beam from the UNILAC accelerator that penetrates a thin carbon foil which is irradiated by an intense laser beam, e.g. the nhelix or PHELIX laser. The foil is turned into a hot plasma while the ions pass through it and the ...

In the Rutherford-Geiger-Marsden experiments, alpha particles were streamed into a thin gold foil in an attempt to prove the plum pudding model of the atom. The results were one of the most striking examples of a discrepant event in scientific history. This demonstration provides the student with a visual sense of what Rutherford and his researchers expected to find, and then what they actually...