نتایج جستجو برای: gmp

تعداد نتایج: 13139  

Journal: :Journal of microbiological methods 2012
Juliane Düvel Daniela Bertinetti Stefan Möller Frank Schwede Michael Morr Josef Wissing Lena Radamm Bastian Zimmermann Hans-Gottfried Genieser Lothar Jänsch Friedrich W Herberg Susanne Häussler

In many bacteria, high levels of the ubiquitous second messenger c-di-GMP have been demonstrated to suppress motility and to promote the establishment of surface-adherent biofilm communities. While molecular mechanisms underlying the synthesis and degradation of c-di-GMP have been comprehensively characterized, little is known about how c-di-GMP mediates its regulatory effects. In this study, w...

Journal: :Journal of bacteriology 2016
Juliane Düvel Sarina Bense Stefan Möller Daniela Bertinetti Frank Schwede Michael Morr Denitsa Eckweiler Hans-Gottfried Genieser Lothar Jänsch Friedrich W Herberg Ronald Frank Susanne Häussler

UNLABELLED High levels of the universal bacterial second messenger cyclic di-GMP (c-di-GMP) promote the establishment of surface-attached growth in many bacteria. Not only can c-di-GMP bind to nucleic acids and directly control gene expression, but it also binds to a diverse array of proteins of specialized functions and orchestrates their activity. Since its development in the early 1990s, the...

Journal: :Journal of bacteriology 2016
Shan-Ho Chou Michael Y Galperin

Cyclic di-GMP (c-di-GMP) synthetases and hydrolases (GGDEF, EAL, and HD-GYP domains) can be readily identified in bacterial genome sequences by using standard bioinformatic tools. In contrast, identification of c-di-GMP receptors remains a difficult task, and the current list of experimentally characterized c-di-GMP-binding proteins is likely incomplete. Several classes of c-di-GMP-binding prot...

Journal: :Jurnal rekayasa dan manajemen agroindustri 2022

The demands of today's consumers are not only for quality but also safe food. To improve product safety, “Industri Kecil Menengah” (IKM) must start implementing the basic level feasibility, namely Good manufacturing practice (GMP). GMP is a feasibility standard that can be used to assess industry feasibility. purpose this study was determine two fish cracker industries located in Sreseh Distric...

Journal: :Molecular Microbiology 2007
Vincent T Lee Jody M Matewish Jennifer L Kessler Mamoru Hyodo Yoshihiro Hayakawa Stephen Lory

Bis-(3',5')-cyclic-dimeric-guanosine monophosphate (c-di-GMP) has been shown to be a global regulatory molecule that modulates the reciprocal responses of bacteria to activate either virulence pathways or biofilm formation. The mechanism of c-di-GMP signal transduction, including recognition of c-di-GMP and subsequent phenotypic regulation, remain largely uncharacterized. The key components of ...

2015
Tian Tian He Hao Hu Yi Tao Wang

Background: Safety, quality and effectiveness of Chinese patent medicine (CPM) are highly relevant to the manufacturing process. However, the level of manufacturing practice (GMP) for CPM as implemented in China is less reported in literatures. Therefore, the aim of this paper was to reveal the implementation status of GMP for CPM in China, in terms of implementation principle, implementation c...

Journal: :Bioscience, biotechnology, and biochemistry 2005
Kouhei Nakajima Norimitsu Tamura Kazuo Kobayashi-Hattori Tadashi Yoshida Yukiko Hara-Kudo Masanari Ikedo Yoshiko Sugita-Konishi Makoto Hattori

The preventive effects of glycomacropeptide (GMP) against intestinal infection were investigated, and conjugates of GMP with xylooligosaccharide (XOS) and carboxymethyldextran (CMD) were prepared by the Maillard reaction to enhance the effect of GMP. The binding ability of GMP to intestinal pathogenic bacteria was evaluated by a binding assay with biotinylated bacteria. GMP showed the ability t...

Journal: :Molecular bioSystems 2013
Yiling Luo Jie Zhou Jingxin Wang T Kwaku Dayie Herman O Sintim

C-di-GMP is a second messenger in bacteria and partly regulates bacterial physiology by binding to class I and II riboswitches. Four class I c-di-GMP riboswitch aptamer candidates, Ct-E88, Cb-17B, Cb-E43 and Cd-630 RNAs, selected from a GEMM RNA sequence motif in the Rfam database, were expressed and experimentally verified to bind to c-di-GMP. The two newly characterized c-di-GMP riboswitches,...

Journal: :The Biochemical journal 1995
D Srivastava D A Fox R L Hurwitz

Knowledge of the kinetics of the rod cyclic GMP phosphodiesterase is essential for understanding the kinetics and gain of the light response. Therefore, the interactions between Mg2+, cyclic GMP, and purified, trypsin-activated bovine rod cyclic GMP phosphodiesterase (EC 3.1.4.17) were examined. The effects of Mg2+ and of cyclic GMP on the rod phosphodiesterase activity were mutually concentrat...

2007
Mikhail Nesterenko André Schiper

We study fault tolerance properties of the group membership problem (GMP) in asynchronous systems. This problem requires each process to determine the processes with which it can communicate. We compare the properties of the GMP and consensus. We define failure sensitivity as the necessary property of a failure detector to enable a solution to the GMP. We demonstrate that the known consensus fa...

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