Celiac disease (CD) has traditionally been thought of as a primarily intestinal disorder, and is now considered the most important autoimmune disease related to gluten intolerance (gluten-sensitive enteropathy) (Freeman et al., 2011). It occurs in genetically susceptible individuals through the ingestion of gluten and is more frequent in women, as is also the case for many autoimmune diseases (...

AMAÇ: Gluten sensitif enteropati, genetik duyarlılığı olan kişilerde glutenli tahıllar buğday, çavdar ve arpanın neden olduğu intestinal ekstraintestinal sistem belirtileri otoimmün özellikler taşıyan sistemik bir hastalıktır.GEREÇ VE YÖNTEM: Bu çalışmada 2000-2012 yılları arasında Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim Dalında tanı konulan takipte 69 hasta retros...

Intestinal permeability to 51Cr-EDTA was examined during the development of gluten sensitive enteropathy in dogs bred from affected Irish setters and reared on a normal wheat containing diet. Comparisons were made with litter mates reared on a gluten free diet and with a control group of age matched, clinically healthy Irish setters reared on the normal diet. Studies at 4, 6, 8, and 12 months o...

Gluten-related diseases were recently classified into three groups according to their physiopathological mechanisms: autoimmunity (celiac disease, dermatitis herpetiformis, gluten ataxia), allergy (wheat allergyrespiratory, alimentary, contact urticary and WDEIA) and no-autoimmune no-allergic (gluten sensitivity)(30). Dermatitis herpetiformis (DH) is an autoimmune blistering cutaneous disease t...

To assess the course of recovery of gluten sensitive enteropathy in adults, histological and functional recovery was studied in 22 patients, aged 20-79 years. Biopsy specimens taken at the time of diagnosis were studied in 20; after adhering to a gluten free diet for nine to 19 (mean 14) months in 14; and after adhering to the same diet for 24-48 (mean 34) months in 10 patients. Histological re...

Celiac disease (celiac sprue or gluten-sensitive enteropathy) is an inflammatory autoimmune disease of the small intestine that occurs in genetically susceptible (HLA DQ2 or DQ8 ) individuals upon exposure to dietary gluten.1 Gluten (gliadin and glutenin, found in wheat, rye, and barley) comprises a family of prolineand glutamine-rich proteins. Celiac disease is common, affecting 0.5 to 1% of t...

UNLABELLED In coeliac disease (CD) there is a gluten-induced small bowel enteropathy leading to malabsorption of various nutrients, vitamins and trace elements. Low levels of serum zinc have been reported in adults with untreated CD. In the present study we related the serum concentration of zinc to the morphology of the small bowel mucosa in 58 children, all under 4 years of age and under inve...

Celiac Disease (CD) or gluten sensitive enteropathy is an autoimmune disorder characterised by variable presentations which respond to exclusion of wheat and other gluten containing products [1]. While exclusion of gluten is the corner stone in the management of this entity, newer therapeutic approaches are now being investigated. These include use of elemental diets, oral prolyl-endopeptidases...