نتایج جستجو برای: glutathione peroxidase gpx

تعداد نتایج: 63916  

Journal: :Physiological research 2005
N Uysal O Acikgoz S Gönenç B M Kayatekin M Kiray A Sönmez I Semin

In a previous study we demonstrated that acute footshock stress increased glutathione peroxidase activity in the prefrontal cortex and striatum of adult male rats. Adolescents may respond differently to stress as life stressors may be greater than at other ages. The present study examined the effects of the acute footshock stress on superoxide dismutase (SOD) and glutathione peroxidase (GPx) en...

ژورنال: Medical Laboratory Journal 2007
Heydari, K, Joshaghani, H. R., Mansoorian, A.R., Marjani, A, Sarikhani,, A,

Abstract Background and objective: Exposure of red blood cells to oxygen radicals can induce Lipid proxidation, hemoglobin damage and hemolysis of erythrocyte .The present study was designed to determine the alteration of plasma lipid peroxidation and erythrocyte Superoxide Dismutase and Glutathione Peroxidase enzyme activities in stored blood and to find out the quantitative alterations and th...

Journal: :The Biochemical journal 1995
S Soboll S Gründel J Harris V Kolb-Bachofen B Ketterer H Sies

Hepatocellular nuclei require glutathione, glutathione S-transferases (GSTs) and Se-dependent glutathione peroxidase (GPx) for intranuclear protection against damage from electrophiles or products of active oxygen. Data so far available from the literature on nuclei isolated in aqueous systems range from glutathione, GSTs and GPx either being absent altogether to being present in quantities in ...

Journal: :Biochimica et biophysica acta 2008
Fei Yan Wen-Kui Yang Xin-Yang Li Ting-Ting Lin Yan-Ni Lun Feng Lin Shao-Wu Lv Gang-Lin Yan Jun-Qiu Liu Jia-Cong Shen Ying Mu Gui-Min Luo

Superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione S-transferase (GST) and glutathione reductase (GR) play crucial roles in balancing the production and decomposition of reactive oxygen species (ROS) in living organisms. These enzymes act cooperatively and synergistically to scavenge ROS, as not one of them can singlehandedly clear all forms of ROS. In order to imitate the sy...

2009
P Sreejith

The short-term action of thyroid hormone tri-iodothyronine (T3) was studied in vivo and in vitro on antioxidant enzyme activities in a teleost Anabas testudineus (Bloch). T3 injection in vivo (200 ng) in normal fish decreased the lipid peroxidation products and increased superoxide dismutase (SOD), catalase and glutathione peroxidase (GPx) activities after 30 min. T3 in vitro (10 M) increased t...

Journal: :American heart journal 2008
Renate Schnabel Edith Lubos Claudia M Messow Christoph R Sinning Tanja Zeller Philipp S Wild Dirk Peetz Diane E Handy Thomas Munzel Joseph Loscalzo Karl J Lackner Stefan Blankenberg

BACKGROUND Selenium is a central determinant of antioxidative glutathione peroxidase 1 (GPx-1) expression and activity. The relevance of selenium supplementation on GPx-1 in coronary artery disease (CAD) needs to be established. We assessed the effect of selenium supplementation on GPx-1 in cell culture and on endothelial function in a prospective clinical trial. METHODS Human coronary artery...

Journal: :Journal of anatolian environmental and animal sciences 2021

In this study, some biochemical responses of Cyfluthrin (CFT), a commercial insecticide in Dreissena polymorpha, were investigated. The 96 hour LC50 value CFT on D. polymorpha was calculated as 553.22 ± 27.3 µg / L. exposed to subletal concentrations (1/20, 1/10 and 1/5 value) for 24 hours. enzyme activities superoxide dismustase (SOD), catalase (CAT) glutathione peroxidase (GPx) determined ind...

2001
Frederick E. Domann Sabina S. Peters

Ebselen (2-phenyl-1, 2-benzisoselenazol-3 (2H)-one) is a glutathione peroxidase mimic that catalyzes the reduction of a hydroperoxide with the oxidation of a thiol. In vitro models indicate that the oxidative protection ebselen affords to cells is due to its glutathione peroxidase (GPx) mimic activity. This paper will describe ebselen’s reactions, detection, and pharmacological potential. Intro...

Journal: :The Journal of biological chemistry 2004
Charlene Bierl Barbara Voetsch Richard C Jin Diane E Handy Joseph Loscalzo

Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing protein with antioxidant properties. GPx-3 deficiency has been associated with cardiovascular disease and stroke. The regulation of GPx-3 expression remains largely uncharacterized, however, and we studied its transcriptional and translational determinants in a cultured cell system. In transient transfections of a renal cell l...

Journal: :international journal of bio-inorganic hybrid nanomaterials 0

supplementation has beneficial effects in immune system and can antioxidant enzymes activity increases during the exercise and protects the tissue against the oxidative stress. l-carnitine is a famous supplement and helps to protect against the oxidative stress during and after intense or prolonged exercise. the aim of this study was to investigate the effect of l-carnitine supplementation on t...

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