The existence of glutamate receptors as important neurotransmitter receptors was not fully accepted until the 1980s. It is now generally agreed that glutamate is the major fast excitatory neurotransmitter in brain, and plays a major role in brain development, affecting neuronal migration, neuronal differentiation, axon genesis, and neuronal survival through its action on the glutamate receptors...

background: the areas of the bed nucleus of the stria terminalis (bst) with a high density of estrogen receptors are involved in cardiovascular regulation and send axonal projections to the rostroventrolateral medulla (rvlm). we aimed to find the contribution of the rvlm to cardiovascular responses elicited by glutamate microinjection into the bst. methods: experiments were done in α-chloralose...

Tea (Camellia sinensis) is widely considered to promote feelings of calming and soothing. This effect attributed L-theanine (L-?-glutamylethylamide) in tea, a non-protein amino acid mainly derived from tea leaves. As naturally occurring structural analogue glutamate, competes for the receptors with glutamate able pass blood-brain barrier exert its relaxation effect. review focuses on L-theanine...