it has been shown that enhanced acid secretion can be suppressed in the rat by systemic administration of glucose. we have recently reported that enhancement of acid secretion as a result of pentagastrin was diminished by intragastric administration of d-glucose. present study was designed to investigate whether intragastric d-glucose influences gastric acid secretion associated with carbachol ...

the effect of blood glucose level changes induced by 24h food deprivation and intraperitoneal (ip) injection of insulin (2iu/kg) and glucose (2gr/kg) was investigated on the pain induced by intraplantar (ipl) injection of formalin (20ml , 5%) in mice. blood glucose level changes were determined by blood sampling from the apex of the tail of mice. ip injection of insulin and 24h food deprivation...

Some plant extracts showed the ability to retard the diffusion of glucose across the dialysis tube. The present study was designed to investigate the effect of aqueous and ethanolic extracts of Teucrium polium (T. polium) on glucose movement across the dialysis tube. The T. polium powder was dissolved in ethanol and distilled water. Then glucose was added to make a final concentration of 0.2 – ...

the hypoglycemic effect of ethanolic extract of casearia esculenta was investigated on alloxan induced diabetic rats. the blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. the ethanolic extract of c. esculenta (250 mg/kg) reduced the blood glucose of normal rat from 85.50±1.22 to 64.67±3.27 mg/dl, 3 h after oral administration of the extract (p<0.05). it also significan...

Received for publication 24 August 1972 and in revised form 2 April 1973. INTRODUCTION The anatomic location of the liver, receiving the entire pancreatic output of insulin prior to its entry into the systemic circulation, and its ability to degrade insulin permits it to play an important role in regulating peripheral insulin concentrations (1). Although increases in peripheral insulin levels h...

It has been shown that those factors which affect gastric acid secretion through the ventromedial and lateral nuclei of hypothalamus, can significantly alter centrally-mediated secretion. There is much evidence that glucose is among these factors that through a central mechanism can decrease induced acid secretion. It appears that this effect is mediated through glucose-sensitive neurons within...

Although Securigera securidaca (Ss) has long been known for its hypoglycemic effect, the precise nature of its effective component(s) and the involved mechanisms have not been investigated yet. This study investigated the effect of chloroformic extract of securigera securidaea seed on fasting serum glucose and glucose tolerance test, body weight, food consumption and liver glycogen content. Chl...

Impaired glucose tolerance has several adverse effects on growing fetus. In this study we evaluated the effect of excessive weight gain during pregnancy on the risk of glucose intolerance in pregnant women. A case-control study was conducted through which the glucose tolerance status after 100 gram oral glucose intake was compared between 60 pregnant women with maximum 10 weeks of gestation and...

the aim of this study is to determine the effect of the aqueous extract of the leaves of eucalyptus globules on blood glucose level in fasted rats, and to find a new medical adjunct to anti-diabetes drugs. the aqueous extract of eucalyptus was administered in various doses (150-400 mg/kg) orally. blood glucose level was checked 2-6 h after treatment. the study showed that oral administration of...