Glucocorticoids are known to affect calcium balance but not thought cause clinically significant hypocalcemia. This case adds a list of isolated reports noting hypocalcemia developing post administration glucocorticoids in patient with hypoparathyroidism, postulating parathyroid hormone deficiency as risk factor decompensated homeostasis.

OBJECTIVES To examine the evidence for the efficacy and glucocorticoid sparing effect of oral anti-leukotrienes taken daily as add-on therapy to inhaled glucocorticoids in patients with asthma. DESIGN Systematic review of randomised controlled trials of children and adults with asthma comparing the addition of anti-leukotrienes or placebo to inhaled glucocorticoids. MAIN OUTCOME MEASURES Th...

The lessons from the Utrecht study on glucocorticoid therapy in early rheumatoid arthritis and of the spin-off and follow-up studies are reviewed. The data indicate that: glucocorticoids are DMARDs, the joint-sparing effect is predominantly on erosions, glucocorticoids do not influence the percentage of patients developing erosive disease, and the gain in joint-sparing effect persists after the...

Glucocorticoids can acutely affect memory processes, with both facilitating and impairing effects having been described. Recent work has revealed that glucocorticoids may affect learning and memory processes by interacting with glutamatergic mechanisms. In this opinion article I describe different glutamatergic pathways that glucocorticoids can affect to modulate memory processes. Furthermore, ...

Conservation physiology proposes that measures of physiological stress (glucocorticoid levels) can be used to assess the status and future fate of natural populations. Increases in glucocorticoids may reflect a more challenging environment, suggesting that the influence of human activities on free-living animals could be quantified by measuring glucocorticoids. Biomedical studies suggest that c...

Glucocorticoids are a class of steroid hormones that are essential to life but cause serious harm in excess. The main clinical features of glucocorticoid excess are due to adverse effects on cells and tissues that arise from a common developmental precursor - the mesenchymal stromal cell (MSC; sometimes referred to as the mesenchymal stem cell). Interestingly glucocorticoids appear essential fo...