Cognitive reserve (CR) is a potential mechanism to cope with brain damage. The aim of this study was to evaluate the effect of CR on a cognitive training (CT) in a group of patients with dementia. Eighty six participants with mild to moderate dementia were identified by their level of CR quantified by the CR Index questionnaire (CRIq) and underwent a cycle of CT. A global measure of cognition m...

OBJECTIVE To examine the relation of type 2 diabetes to the level of function in five different cognitive systems in older individuals without dementia. RESEARCH DESIGN AND METHODS Participants were 882 older men and women without dementia participating in the Rush Memory and Aging Project, a longitudinal clinical-pathological study of aging and dementia. They underwent uniform evaluations, w...

BACKGROUND Lipid-lowering medications (LLMs) and especially statin drugs can delay cognitive decline and dementia onset in individuals with and without mild cognitive impairment (MCI) at baseline. METHODS A longitudinal, observational study was conducted of 3069 cognitively healthy elderly patients (≥75 years of age) who were enrolled in the Ginkgo Evaluation of Memory Study. The primary outc...

1 NHS Executive. The new NHS: a national framework for assessing performance. London: Department of Health, 1998. 2 Bindman A B, Grumbach K, Osmond D, Komarony M, Vranizan K, Lurie N, et al. Preventable hospitalisations and access to health care. JAMA 1995;274:305-11. 3 Reid FDA, Cook D, Majeed FA. Variation in hospital admission rates between general practices: cross sectional study. BMJ 1999;...

PURPOSE To describe the efficacy and safety of hydromorphone extended-release tablets (OROS hydromorphone ER) during dose conversion and titration. PATIENTS AND METHODS A total of 459 opioid-tolerant adults with chronic moderate to severe low back pain participated in an open-label, 2- to 4-week conversion/titration phase of a double-blind, placebo-controlled, randomized withdrawal trial, con...

The aim of this paper is to discuss the potential benefit of corpus analysis, a (partly) empirical method from linguistics, for philosophy� ‘Corpus analysis’ is not only the name of the method, but also a rough description of it, because the method consists in analysing data taken from linguistic text corpora� In linguistics, using such text corpora is an established practice� A fair number of ...

Consistent with the worldwide demographic trend of population aging, dementia is expected to become a burgeoning public health problem in Asian populations.Thus, there is a pressing need for reliable and valid methods of dementia diagnosis and staging that are applicable in heterogeneous Asian populations. The Clinical Dementia Rating (CDR) is an informant-based global assessment scale with est...