OBJECTIVE To determine the frequency, clinical presentation and management outcomes of Gestational Trophoblastic Disease (GTD). STUDY DESIGN Descriptive case series. PLACE AND DURATION Department of Gynaecology and Obstetrics, Liaquat University of Medical and Health Sciences, Jamshoro, from March 2003 to March 2004. PATIENTS AND METHODS The case records of all the gestational trophoblast...

placental site trophoblastic tumor (pstt) is the rare variant of gestational trophoblastic diseases (gtd), which differs histologically and immunologically from gtd. diagnosis of pstt is often difficult and delayed. in most cases, diagnosis is not possible until the surgery is performed. the most therapeutic choice is hysterectomy and it is usually successful. here we report two cases of pstt.

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...

  Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of PST...

AIMS To assess the expression profile of the activated form of signal transducer and activator of transcription (Stat)3 in gestational trophoblastic disease (GTD) and correlate the findings with clinicopathological parameters. METHODS AND RESULTS By immunohistochemistry, both cytoplasmic and nuclear expression of p-Stat3-Ser(727) was demonstrated in 88 trophoblastic tissues, including placent...

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...

Transformations are a common technique used to linearize data so that simple linear regression can be applied. A common transformation used is the logarithmic transformation. This transforms data that follows an exponential pattern so that a straight line can be fit to it. In this study human chorionic gonadotropin (hCG) levels in women with gestational trophoblastic disease (GTD), which are kn...

Gestational trophoblastic disease (GTD) is a pregnancy disorder due to an abnormality of the placenta, such as enlargement chorionic villi. The spectrum GTD may range from benign malignant. Characteristics gestational have been discussed in literature. This study characteristics that resulted previous studies and relationship those disease. results this revealed there were five national referra...

Gestational trophoblastic disease (GTD) is a condition that develops from abnormal proliferation of placental trophoblasts. A rare division GTD partial mole with co-existing live fetus-a also referred to as “sad fetus syndrome” We report case 24-year-old, primigravida 26 weeks gestational age single intrauterine gestation coexisting molar pregnancy who had spontaneous preterm delivery at 27 wee...