Background: Gestational diabetes mellitus affects 3-5% of all human pregnancy.Studies reported the neurotoxic effect of gestational diabetes on cerebellarand spinal cord in rat offspring. This study was conducted to determine the effect of gestational diabetes on astrocyte density in the cerebellum of rat offspring. Materials and Methods: In this experimental study, 30 Wistar rats dams were ran...

introduction: diabetes mellitus is associated with nervous system alterations in both human and animal models. this study was done to determine the effect of gestational diabetes on the purkinje and granular cells in the cerebellum of rat offspring.  methods: 10 wistar rats dams were randomly allocated in control and diabetic group. the experimental group received 40 mg/kg/body weight of strept...

The aim of this observational study was to evaluate screening and progression of diabetic retinopathy during pregnancy in women with pregestational diabetes attending five antenatal centres along the Irish Atlantic seaboard. An adequate frequency of screening was defined as at least two retinal evaluations in separate trimesters. Progression was defined as at least one stage of deterioration of...

Type 1 and 2 diabetes decrease the frequencies and functional capacities of circulating angiogenic cells (CAC). Diabetes also elevates gestational complications. These observations may be interrelated. We undertook pilot studies to address the hypothesis that preconception diabetes deviates known gestational increases in CACs. Cross-sectional study of type 1 diabetic, type 2 diabetic and normog...

Background: Research says that diabetes may develop in over 10% of non-diabetic pregnant women. Diabetes which generally occurs late in second trimester and third trimester of pregnancy, it is called gestational diabetes. Overweight or suffering from obesity before pregnancy is type 2 diabetes risk factor. In most cases, diabetic symptoms disappear after delivery. HLA-G has an important role bo...

background: although gestational diabetes is a well-known cause of pregnancy complications, its epidemiology in iran has not been studied systematically. the aim of this review of published data was to describe epidemiology of gestational diabetes in iran. methods: we searched medline, www.sid.ir, www.magiran.com, www.iranmedex.com, and www.irandoc.ac.ir sites through march 2009, and examined t...

Gestational diabetes mellitus is described as glucose intolerance at various degrees that is first detected during pregnancy. In diabetic complications, there are changes in placental function, particularly with respect to intake, transmit, and utilization of glucose, and also in glycolysis and glycolytic enzymes. The placenta possibly plays a critical role in protecting the fetus from adverse ...

presence of maternal diabetes mellitus (dm) during pregnancy has important consequences for both mother and child. to determine maternal and fetal/neonatal complications of gestational dm and compare them with pre-gestational dm, a prospective study was performed in 100 diabetic women delivered in our hospital from january 2001 to april 2002. pregnancy outcome in 27 women with gestational dm an...