Spherical viral shells with icosahedral symmetry have been considered as quasicrystalline tilings. Similarly to known Caspar–Klug quasi-equivalence theory, the presented approach also minimizes the number of conformations necessary for the protein molecule bonding with its neighbors in the shell, but is based on different geometrical principles. It is assumed that protein molecule centers are l...

Digital Preservation deals with ensuring that digital data stored today can be read and interpreted tens or hundreds of years from now. At the heart of any solution to the preservation problem lies a storage component. This paper characterizes the requirements for such a component, defines its desirable properties and presents the need for preservationaware storage systems. Our research is cond...

Caspar Bowden ([email protected]) is the author of a recent DLTR article, Closed Circuit Television for Inside Your Head: Blanket Traffic Data Retention and the Emergency Anti-Terrorism Legislation. He is the Director of the Foundation for Information Policy Research (http://www.fipr.org), an independent non-profit think-tank that undertakes research on the interaction between information technology ...

The 2008 Leroy P. Steele Prizes were awarded at the 114th Annual Meeting of the AMS in San Diego in January 2008. The Steele Prizes were established in 1970 in honor of George David Birkhoff, William Fogg Osgood, and William Caspar Graustein. Osgood was president of the AMS during 1905–1906, and Birkhoff served in that capacity during 1925–1926. The prizes are endowed under the terms of a beque...

MOTIVATION DNA microarrays allow the simultaneous measurement of thousands of gene expression levels in any given patient sample. Gene expression data have been shown to correlate with survival in several cancers, however, analysis of the data is difficult, since typically at most a few hundred patients are available, resulting in severely underdetermined regression or classification models. Se...

The Anopheles gambiae immune response against Plasmodium falciparum, an etiological agent of human malaria, has been identified as a source of potential anti-Plasmodium genes and mechanisms to be exploited in efforts to control the malaria transmission cycle. One such mechanism is the Imd pathway, a conserved immune signaling pathway that has potent anti-P. falciparum activity. Silencing the ex...