Today, chronic viral hepatitis is considered as a public health problem in the world. Totally, 5% of the world population, especially in Asia and Africa suffer from this problem. The prevalence of acute hepatitis in America is 0.1-0.2 percent, 50% of those with hepatitis C (HCV) and 5-10% of them with hepatitis B (HCV) develop chronic hepatitis. Determining HBV and HCV genotypes is important to...

background: ccl22/mdc is a cc chemokine with a critical role in regulation of the immune balance in physiological condition. ccl22/ccr-4 ligation has been documented to participate in the migration of regulatory t (treg) cells and th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. objective: to investigate the association of a single...

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality. The aim of this study was to determine the relation between FOLH1 and DISC1 genes polymorphism in patients with schizophrenia in Iran. In this study, 50 patients with schizophrenia and 50 healthy controls were evaluated. PCR-RFLP was used for FOLH1 gene and Tetra-ARMS for the DIS...

The aim of the present study was to screen the genotype profile of bovine kappa-casein gene among Frieswal (HF × Sahiwal) crossbred cattle developed in India. A total number of two hundred Frieswal cows were evaluated for HinfI RFLP based genotyping of kappa-casein gene. We observed that only two genotypes (AA and AB) exist among the studied population with the genotype frequency of 0.58 (n=117...

background il28b polymorphism is recognized as one of the most prominent predictors of hepatitis c spontaneous and treatment-induced clearance. interestingly, the favorable genotypes of il28b are found to be more frequent in asian ethnicity than caucasian and african populations, respectively. a few studies reported that there is a mysterious association between the il28b polymorphism and the h...

The influence of melatonin receptor 1A gene on litter size was studied in 150 ewes from Zel (n=100) and Naeini (n=50) sheep breeds. Two restriction fragment length polymorphism (RFLP) analyses were done to determine all genotypes occurring by variations at MnlI and RsaI restriction sites. The M and C were the most frequent alleles in both of these breeds. The MM genotype was predominant in Zel ...

tumor necrosis factor alpha-inducible protein 3 (tnfaip3) gene polymorphisms have been reported to be associated with the susceptibility to several immune-related diseases. here we investigated the effect of tnfaip3 gene polymorphisms on the risk of allergic rhinitis (ar) in a chinese han population. the case-control study included 540 ar patients and 524 healthy controls. genotyping for tnfaip...