results phylogenetic analysis of the partial ns5b region demonstrated the relatedness of isolate fsm165 to the new subtype reported from iran in 2006. moreover, some core/e1 and ns5b sequences that had a high level of similarity with fsm165 isolate were found through searching the hcv database. these sequences were previously either misclassified or could not be accurately classified. phylogene...

background: endometriosis is a female health disorder that occurs when cells from the lining of the uterus grow in other areas of the body. the cause of endometriosis is unknown. objective: the purpose of this study was to investigate tp53 gene codon 72 polymorphism in women with endometriosis and compared it with healthy samples in isfahan. materials and methods: we undertook a case-control st...

background: interaction between killer cell immunoglobulin-like receptors (kir) and human leukocyte antigen (hla) class i molecules is important for regulation of natural killer (nk) cell function. objective: the aim of this study was to investigate the impact of compound kir-hla genotype on susceptibility to acute leukemia. methods: cohorts of iranian patients with acute myeloid leukemia (aml;...

blastocystis hominis is a protozoan parasite which mainly found in human fecal samples both from symptomatic patients and asymptomatic population in developing countries. in this study we reported a patient referred to gi clinic with abdominal pain, nausea, vomiting, fever for 2 or 3 days and passed watery stools because of blastocystis sp. subtype 2 infection.

background: molecular epidemiology of measles virus (mv) is important, not only to measure the success of measles vaccination programs but also to monitor the circulation and elimination of the virus worldwide. in this study, we compared mv obtained from patients before the 2003 mass vaccination mr campaign and viruses detected after 2003 until 2008 in iran. methods: the nucleoprotein (n) gene ...

congenital toxoplasmosis is associated with variable complications including encephalitis, microcephaly, hydrocephaly, hepatitis, lymphadenopathy and even intrauterine death. presence of toxoplasma gondii in human placenta may induce congenital infection. the aim of this study was to determine the genotypes of toxoplasma gondii infection in human spontaneous aborted fetuses in shiraz, south of ...

conclusions the main and frequent hbv genotype among azerbaijani patients with chronic hepatitis b virus infection was genotype d followed by genotype a. results the mean age of patients was 35.9 ± 11.7 years (19-66). of 103 patients, 72 (69.9%) were male. in the present study, the predominant hbv genotype was d (93.2%) followed by genotype a (5.8%) and concurrent infection with a and d genotyp...

background: genetic polymorphisms of cytochrome p450 in humans are the main cause of differences in the metabolism. the allele and genotype frequencies of cyp2c19 and cyp2c9 have been studied in some iranian populations. the aim of present study was to examine the frequencies of cyp2c18m1, and cyp2c18m2, alleles in the mazandarani ethnic group among iranian population. materials and methods: in...

conclusions the majority of hiv-infected persons in the city of kashan were also hcv positive. genotype 1 was the predominant type, alongside subtype a. considering the high prevalence of hcv among the hiv-infected persons, as well as the impact of occupation, education, illicit drug use, and imprisonment on the incidence of both infections, health policy makers must introduce health programs a...