Gene pool of every organism has shown a wide occurrence of genetic variations. Variations have not only been associated with diseases like cancer, turner syndrome, sickle cell anaemia, cystic fibrosis etc., but some of them have even been proved to be beneficial in certain cases like for increasing bone density, lowering down cholesterol level, and for developing malaria resistance. Genetic var...

Background: Gastric cancer (GC) has an apparent hereditary component. However, in a large fraction of gastric cases, no known genetic syndrome or family history can be identified, suggesting the presence of ‘missing heritability’ in GC etiology. Genome-wide association studies (GWAS) and traditional candidate gene studies have both led to the identification of multiple replicable common genetic...

We investigated the properties of cellular automata with three or more possible states, represented by colors. For the simulation, the Pygame tool was used. Our hypothesis was that the system would be overall chaotic, with periods of stability, but we found that the system instead converges to a stable period-2 limit cycle, indicated by a checkerboard pattern in the simulation. Mutation can hav...

background: considering a few studies on the genetic basis of the cystinuria in the middle east and the population-specific distribution of mutations in the slc3a1 , we tried to find genetic variants in three exons (1, 3, and 8) of slc3a1 . materials and methods: in this study, exons 1, 3, and 8 of slc3a1 gene of 25 unrelated cystinuria patients searched for genetic variations by polymerase cha...

meriones crassus, meriones persicus, and meriones libycus from different areas of khorasan provinces and yazd province were studied by use of random amplified dna polymorphism (rapd) technique. dna samples were analyzed by use of nine primers. genetic distance among samples varied between 0.24 and 0.78. dendrogram designed on the base of genetic distance shows separation of these species. in th...

recent studies have provided evidence that common genetic variations could account for a proportion of leukemia in adult or children. to evaluate the contribution of candidate gene association studies to the understanding of genetic susceptibility to acute lymphoblastic leukemia we conducted a systematic review from published studies. the polymorphisms of genes encoding carcinogen-metabolizing ...

abstract background: it is well recognized that different patients respond in different ways to medications. the inter-individual variations are greater than the intera- individual variations, a finding consistent with the notion that inheritance is a determinant of drug responses. the recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the h...

stroke is the third cause of death in the world after the cancer and cardiovascular disease. . it has been shown that stroke in northeast of iran occurs approximately one decade earlier than in western countries. reasons for the high stroke incidence among persian are not yet clear. it is the first gene-association study in persian population, which determines the relationship between 25 gene v...

 ABSTRACT Background: It is well recognized that different patients respond in different ways to medications. The inter-individual variations are greater than the intera- individual variations, a finding consistent with the notion that inheritance is a determinant of drug responses. The recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the ...