نتایج جستجو برای: genetic translocation
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The narrow genetic background restricts wheat yield and quality improvement. The wild relatives of wheat are the huge gene pools for wheat improvement and can broaden its genetic basis. Production of wheat-alien translocation lines can transfer alien genes to wheat. So it is important to develop an efficient method to induce wheat-alien chromosome translocation. Agropyroncristatum (P genome) ca...
AbstractChromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. Although X-autosome translocations are frequently associated with streak gonads and clinical features of the Turner syndrome, the majority of X-autosome carriers may present with a variable phenotype, developmental delay, and recognizable X-linked syndrome ...
Physicians are families' best counsellers, and genetic counseling is one of the most important and delicate aspects of medicine. Genetic disorders are the third most common problems of mankind after infectious diseases and malnutrition. 10% of neonatal and 25% of pediatric mortalities are some how related to congenital and genetic disturbances. Genetic disorders are categorized in four major gr...
Ewing sarcoma is the second most common involving bones in children and adolescents. Published data on clinical features, morphology, translocation follow-up of patients with from India, sparse. Objectives this study were to analyse clinico-pathologic features compare status, BCoR immunohistochemistry, treatment survival. 406 cases diagnosed Department Pathology, Christian Medical College, Vell...
Abstract Translocation is an important conservation tool for reducing the probability of extinction threatened plants. It also becoming increasingly common management practice, as habitats are destroyed and climate change pushes more plants beyond limits their tolerances. Here we outline case informing translocations with dedicated genomic data. We begin by describing principles using genetic a...
acute lymphoblastic leukemia(all) is due to early stage arrest of lymphoblast development. the translocation of philadelphia (ph) chromosome occurs as a result of the bcr-abl fusion gene, which constitutively produced activated tyrosine kinase. this gene fusion is an important indicator for prognosis in all and is associated with poor overall survival and remission duration. bcr-abl could inter...
Mutations within the signal sequence of cytochrome f (cytf) in Chlamydomonas inhibit thylakoid membrane protein translocation and render cells nonphotosynthetic. Twenty-seven suppressors of the mutant signal sequences were selected for their ability to restore photoautotrophic growth and these describe six nuclear loci named tip1 through 6 for thylakoid insertion protein. The tip mutations rest...
A proportion of MYC translocation positive diffuse large B-cell lymphomas (DLBCL) harbour a BCL2 and/or BCL6 translocation, known as double-hit DLBCL, and are clinically aggressive. It is unknown whether there are other genetic abnormalities that cooperate with MYC translocation and form double-hit DLBCL, and whether there is a difference in clinical outcome between the double-hit DLBCL and tho...
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