objective: estimation of genetic parameters for kleiber ratio (kr) and genetic trends for pre-weaning weights of arabi sheep has not been previously conducted.methods: data and pedigree information were collected at the khuzestan ramin agricultural and natural resources university, animal science research station, located in southwest iran, from 2001 to 2008. (co)variance components and corresp...

Nonnormal phenotypic distributions introduce significant problems in the estimation and selection of genetic models. Here, a semiparametric maximum likelihood approach to analyzing nonnormal phenotypes is described. In this approach, distributions are explicitly modeled together with genetic and environmental effects. Distributional parameters are introduced through mixture constraints, where t...

Population genetics is a powerful tool for measuring important larval connections between marine populations [1-4]. Similarly, oceanographic models based on environmental data can simulate particle movements in ocean currents and make quantitative estimates of larval connections between populations possible [5-9]. However, these two powerful approaches have remained disconnected because no gene...

OBJECTIVES To determine the relative contributions of genetic and environmental factors on daytime and nighttime continuous sleep duration at 6, 18, 30, and 48 months of age, and to identify different subgroups of children who followed different daytime and nighttime sleep duration trajectories and to investigate their etiology. METHODS The current study included 995 twins (405 monozygotic an...

The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...

objective: the main objective of this research was estimation of genetic parameters for five consecutive measurements of egg weights in isfahan fowl using multi trait model and random regression models. methods: the statistical models included generation-hatch as a fixed effect, weeks of age as a covariate and additive genetic and individual permanent environmental effects as random effects. th...