نتایج جستجو برای: genetic damage index gdi

تعداد نتایج: 1200367  

Journal: :Gait & posture 2017
Christina Bickley Judi Linton Nancy Scarborough Elroy Sullivan Katy Mitchell Douglas Barnes

AIM The purpose of this study was to introduce a standardized set of surgical technical achievement goals (TAGs) as part of a comprehensive outcome assessment model for children with spastic cerebral palsy (CP) undergoing orthopaedic surgical intervention to improve gait. Examination of relationships of these surgical goals to the Gait Deviation Index (GDI) and use of two assessments in tandem ...

2016
Merete A. Malt Ånen Aarli Bård Bogen Jonas M. Fevang

AIM The Gait Deviation Index (GDI) is a score derived from three-dimensional gait analysis (3DGA). The GDI provides a numerical value that expresses overall gait pathology (ranging from 0 to 100, where 100 indicates the absence of gait pathology). The aim of this study was to investigate the association between the GDI and different levels of gross motor function [defined as the Gross Motor Fun...

Journal: :PLoS ONE 2007
Michela Felberbaum-Corti Etienne Morel Valeria Cavalli Francis Vilbois Jean Gruenberg

BACKGROUND Small GTPases of the Rab family can cycle between a GTP- and a GDP-bound state and also between membrane and cytosol. The latter cycle is mediated by the Guanine Nucleotide Dissociation Inhibitor GDI, which can selectively extract GDP-bound Rab proteins from donor membranes, and then reload them on target membranes. In previous studies, we found that capture of the small GTPase Rab5,...

Journal: :Annales Universitatis Mariae Curie-Skłodowska, sectio H, Oeconomia 2018

2014
Zhiwu Dan Ping Liu Wenchao Huang Wei Zhou Guoxin Yao Jun Hu Renshan Zhu Baorong Lu Yingguo Zhu

The application of heterosis (hybrid vigor) has brought great success to plant breeding, particularly of hybrid rice, achieving significant yield increases. Attempts to explore the heterosis of inter-subspecific hybrids between indica and japonica rice, which result in even greater yield increases, have greatly increased in the past decades. However, because of the reduced seed setting rate in ...

2012
Nouhad Raissouni Andrey Kolesnikov Radhika Purushothaman Sunil Sinha Sonal Bhandari Amrit Bhangoo Shahid Malik Revi Mathew Jean-Patrice Baillargeon Maria Isabel Hernandez Michael Rosenbaum Svetlana Ten David Geller

BACKGROUND First-degree relatives (FDRs) of women with PCOS are at increased risk for impaired insulin sensitivity and diabetes mellitus. Glucose tolerant FDR have evidence of insulin resistance and hyperinsulinemia prior to emergence of frank PCOS. AIM To study insulin dynamics parameters in the early adolescent FDR of women with PCOS. METHODS This is a cross-sectional study involving 18 a...

Journal: :Journal of bodywork and movement therapies 2013
Danielli Souza Speciali Elaine Menezes de Oliveira Nadia Maria dos Santos Fernando Vieira Pereira América Cristina Fracini Thiago Yukio Fukuda Claudia Santos Oliveira João Carlos Correa Paulo Roberto Garcia Lucareli

Three-dimensional gait analysis (3DGA) is an important element in the quantitative evaluation of gait in subjects with Parkinson's disease (PD). Indexes, such as the Gait Deviation Index (GDI), have recently been proposed as a summary measure of gait. The aim of the present study was to investigate the effectiveness of the GDI and spatiotemporal variables in the quantification of changes in gai...

2010
Anna Y. Lee Richard Perreault Sharon Harel Elodie L. Boulier Matthew Suderman Michael Hallett Sarah Jenna

BACKGROUND The symptoms of numerous diseases result from genetic mutations that disrupt the homeostasis maintained by the appropriate integration of signaling gene activities. The relationships between signaling genes suggest avenues through which homeostasis can be restored and disease symptoms subsequently reduced. Specifically, disease symptoms caused by loss-of-function mutations in a parti...

Journal: :Orthopaedics & traumatology, surgery & research : OTSR 2013
N Khouri E Desailly

INTRODUCTION In children with cerebral palsy the abnormal activity of the rectus femoris (RF) during the swing phase results in "stiff-knee gait". Transferring the RF to a knee flexor tendon improves this stiffness. The effect may be limited by adhesions from scar tissue or from angular deviations along the surgically created muscle tendon route. HYPOTHESIS The goal of this study was to asses...

Journal: :Gaceta sanitaria 2013
Elisa Chilet-Rosell M Teresa Ruiz-Cantero José Fernández Sáez Carlos Alvarez-Dardet

OBJECTIVES It is well known that sex differences in analgesic prescription are not merely the logical result of greater prevalence of pain in women, since this therapeutic variability is related to factors such as educational level or social class. This study aims to analyse the relationship between analgesic prescription and gender development in different regions of Spain. METHODS Cross-sec...

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