From the unicellular to the more complex pluricellular organism needs to process the signals from its environment to survive. The computation science has already observed, that fact could be demonstrated remembering the artificial neural networks (ANN). This computation tool is based on the nervous system of the animals, but not only the nervous cells process information in an organism. Every c...

The pattern of gene expression in the phenotype of an organism is determined in part by the dynamical attractors of the organism’s gene regulation network. Changes to the connections in this network over evolutionary time alter the adult gene expression pattern and hence the fitness of the organism. However, the evolution of structure in gene expression networks (potentially reflecting past sel...

Toward the goal of understanding system properties of biological networks, we investigate the global and local regulation of gene expression in the Saccharomyces cerevisiae metabolic network. Our results demonstrate predominance of local gene regulation in metabolism. Metabolic genes display significant coexpression on distances smaller than the average network distance, a behavior supported by...