We obtain the expressions for sectional curvature, holomorphic sectional curvature, and holomorphic bisectional curvature of a GCR-lightlike submanifold of an indefinite Kaehler manifold. We discuss the boundedness of holomorphic sectional curvature of GCR-lightlike submanifolds of an indefinite complex space form. We establish a condition for a GCR-lightlike submanifold of an indefinite comple...

Gross chromosomal rearrangements (GCRs) have been observed in many cancers. Previously, we have demonstrated many mechanisms for suppression of GCR formation in yeast. However, pathways that promote the formation of GCRs are not as well understood. Here, we present evidence that the Rad1-Rad10 endonuclease, which plays an important role in nucleotide excision and recombination repairs, has a no...

Unbiased forward genetic screens for mutations causing increased gross chromosomal rearrangement (GCR) rates in Saccharomyces cerevisiae are hampered by the difficulty in reliably using qualitative GCR assays to detect mutants with small but significantly increased GCR rates. We therefore developed a bioinformatic procedure using genome-wide functional genomics screens to identify and prioritiz...

For a single semantic meaning, various linguistic expressions exist the Mainland China, Hong Kong and Taiwan variety of Mandarin Chinese, a.k.a., the Greater China Region (GCR). Differing from the current bilingual word alignment corpus, in this paper, we have constructed two monolingual GCR corpora. One is a 11,623-triple GCR word dictionary corpora which is automatically extracted and manuall...

The Galactic cosmic ray (GCR) intensity has been postulated by others to vary cyclically with a peak to valley ratio of ∼3:1, as the Solar System moves from the Spiral Arm to the Inter-Arm regions of the Galaxy. These intensities have been correlated with global temperatures and used to support the hypothesis of GCR induced climate change. In this paper we show that the model used to deduce suc...

[1] On 20 August 2006 a Forbush decrease observed at Polar in the Earth’s magnetosphere was also seen at the INTEGRAL spacecraft outside the magnetosphere during a very active time in the solar wind. High-resolution energetic particle data from ACE SIS, the Polar high-sensitivity telescope, and INTEGRAL’s Ge detector saturation rate, which measures the galactic cosmic ray (GCR) background with ...

Allergen exposure can confound the management of asthma. To understand the potential mechanisms by which allergens increase the steroid requirements in atopic asthmatics, we examined the effects of allergens on glucocorticoid receptor (GCR) binding affinity and glucocorticoid (GC) responsiveness of peripheral blood mononuclear cells (PBMC) from atopic asthmatics. A significant reduction (p < 0....

BACKGROUND Polycystic ovary syndrome (PCOS) is characterized by ovarian dysfunction. The association with obesity and insulin resistance is well established. Steroid hormones play a central role in the regulation of both ovarian function and body composition. This study aims to assess the influence of known functional polymorphisms in genes that are responsible for the production, metabolism an...

BACKGROUND German cockroach (GCr) allergens induce IgE responses and may cause asthma. Commercial GCr allergen extracts are variable and existing assays may not be appropriate for determining extract composition and potency. OBJECTIVE Our aim was to develop a multiplex antibody/bead-based assay for assessment of GCr allergen extracts. METHODS Single chain fragment variable (scFv) antibodies...

For radiobiology research on the health risks of galactic cosmic rays (GCR) ground-based accelerators have been used with mono-energetic beams of single high charge, Z and energy, E (HZE) particles. In this paper, we consider the pros and cons of a GCR reference field at a particle accelerator. At the NASA Space Radiation Laboratory (NSRL), we have proposed a GCR simulator, which implements a n...