نتایج جستجو برای: gastrointestinal transit

تعداد نتایج: 125006  

Mohammad Khaksari, Nader Shahrokhi Zakieh Keshavarzi

Objective(s):This study was carried out to investigate the effects of COX-2 selective inhibitor (Celecoxib) or non-selective COX inhibitor (Ibuprofen) on gastrointestinal motility. Materials and Methods: The rats were randomly divided into five groups including: intact, sham, traumatic brain injury (TBI) group (intact rats under TBI), Celecoxib group (10 mg/kg), Ibuprofen group (10 mg/kg). Rats...

K Jafari M Faghihi M Hamzehloo M Keshavarz Sh Gharibzadeh SM Karimian

Introduction: In this study, the effects of black tea extract of Iranian tea plant (Camellia sinensis var sinensis) and its polyphenolic pigment thearubigins were investigated on mice intestinal transit time. Method: Thearubigins were isolated by liquid-liquid fraction method. The effects of black tea extract and isolated thearubigins on intestinal propulsion were measured by charcoal propulsio...

2015
Tine Gregersen Anne-Mette Haase Vincent Schlageter Henning Gronbaek Klaus Krogh

BACKGROUND/AIMS The paucity of knowledge regarding gastrointestinal motility in patients with neuroendocrine tumors and carcinoid diarrhea re-stricts targeted treatment. 3D-Transit is a novel, minimally invasive, ambulatory method for description of gastrointestinal motility. The system has not yet been evaluated in any group of patients. We aimed to test the performance of 3D-Transit in patien...

Journal: :EBioMedicine 2016
Susanna Every-Palmer Mike Nowitz James Stanley Eve Grant Mark Huthwaite Helen Dunn Pete M Ellis

BACKGROUND Gastrointestinal side effects are particularly common with clozapine and occur with other antipsychotics, ranging from mild constipation to fatal bowel obstruction and/or ischemia. While this adverse-effect spectrum has been attributed to 'gastrointestinal hypomotility', gastrointestinal transit times in antipsychotic-treated patients have not previously been measured, making this me...

2017
I M Balsa W T N Culp K J Drobatz E G Johnson P D Mayhew S L Marks

BACKGROUND Prophylactic gastropexy has been promoted as a means of preventing gastric volvulus during gastric dilatation and volvulus (GDV) syndrome. Little is known about the impact of gastropexy on gastrointestinal transit time. HYPOTHESIS Laparoscopic-assisted gastropexy (LAG) will not alter gastrointestinal transit times when comparing gastric (GET), small and large bowel (SLBTT), and who...

Journal: :Biological and Pharmaceutical Bulletin 2002

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2001
H P Lefebvre J P Ferré A D Watson C A Brown J P Serthelon V Laroute D Concordet P L Toutain

Although gastrointestinal complications are common in patients with renal disease, the effects of renal dysfunction on bowel motility and gut transit times are not well known. We assessed gastrointestinal electromyographic activity, gastric emptying rate, orocolonic transit time, oroanal transit time, and xylose absorption before and after surgically inducing a 66% decrease in glomerular filtra...

Journal: :Gut 1999
E P Bouras M Camilleri D D Burton S McKinzie

BACKGROUND Prucalopride (R093877) is a selective and specific 5HT4 agonist, the first of a new chemical class of benzofurans, with gastrointestinal prokinetic activities in vitro. AIMS To evaluate the effects of prucalopride on gastrointestinal and colonic transit. METHODS A validated scintigraphic technique was used to measure gastrointestinal and colonic transit over 48 hours in 50 health...

Journal: :Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2011
S S C Rao M Camilleri W L Hasler A H Maurer H P Parkman R Saad M S Scott M Simren E Soffer L Szarka

BACKGROUND Disorders of gastrointestinal (GI) transit and motility are common, and cause either delayed or accelerated transit through the stomach, small intestine or colon, and affect one or more regions. Assessment of regional and/or whole gut transit times can provide direct measurements and diagnostic information to explain the cause of symptoms, and plan therapy. PURPOSE Recently, severa...

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