The rapidly progressive infections of muscle brought about by some members of the genus Clostridium have been investigated by a number of workers during the past ten years. In general, such investigations fell into three groups: investigations of the clostridia found in war wounds and the factors that affect their growth; investigations of the exocellular toxins produced by the pathogenic clost...

While the use of x-rays to treat patients with gas gangrene ended in the early 1940's with the advent of antibiotics, x-ray had been widely accepted as a useful and highly effective treatment for this condition. The present paper re-assesses the historical foundations of this belief, the quality of the data, use of confirmatory animal models, and underlying mechanisms that might account for the...

INTRODUCTION Gas gangrene is most often caused by Clostridium perfringens infection. Gas gangrene is a medical emergency that develops suddenly. The mortality rate is higher with trunk involvement than with involvement of the extremities, which carries a better prognosis. With respect to vertebral involvement, there are few reports in the literature. The purpose of this paper is to report a ver...

BACKGROUND Gas gangrene is a relatively rare event that is typically associated with history of trauma. A non-traumatic history of gas gangrene has been associated with Clostridium septicum and cecal malignancy. CASE PRESENTATION We present a case of a 54-year-old male patient who presented with myonecrosis secondary to Clostridium septicum septicemia and an occult cecal carcinoma. CONCLUSI...

BACKGROUND Spontaneous gas gangrene is necrosis of muscles in the absence of trauma, causing an acutely painful and potentially fatal condition. However, the occurrence of this condition in Crohn's disease has been very rarely documented. CASE REPORT In this extremely rare case we describe an occurrence of spontaneous gas gangrene, in a known case of Crohn's disease. The patient presented wit...

Clostridium septicum is a bacterial species associated with gas gangrene in both humans and animals. Although not usually a pathogen in humans, it has been implicated in some cases of abscesses and bacteremia. We now report the first case of pericarditis with mycotic aneurysm due to C. septicum.

Clostridial myonecrosis is most often seen in settings of trauma, surgery, malignancy, and other underlying immunocompromised conditions. Since 1953 cases of gas gangrene have been reported in orthopaedic patients including open fractures, closed fractures, and orthopaedic surgeries. We present a case of 55-year-old obese woman who developed rapidly progressive gas gangrene in her right leg acc...