Introduction. Garlic (Allium sativum) is believed to have been originated from Central Asia over 6,000 years ago, but has spread to almost everywhere long time ago. Garlic is the edible bulb of the lily family, Liliaceae. It is a relative of the onion and leek, and other related species containing the aromatic sulfur-based compounds, which contribute to the characteristic odor and taste, as wel...

BACKROUND The medicinal use of garlic is much older than its usage as a food. The medical importance of garlic comes forward for its sulfur-containing components. In this study, it was aimed to compare Kastamonu garlic type with Chinese garlic type based on their aroma profiles. MATERIALS AND METHODS Fresh Kastamonu garlic samples harvested from Kastamonu region of Turkey and Chinese garlic s...

Plant-mediated synthesis of metal oxide nanoparticles is a promising alternative to the traditional method of physical and chemical synthesis. In this paper, we report the green synthesis of zinc oxide nanoparticles (ZnONPs) by a biological method. During the study, Zinc oxide nanoparticles were synthesized by Allium sativum skin (garlic skin) extract. Formation of zinc oxide nanoparticles has ...

Cancer prevention through intake of biologically active natural products appears to be an accessible way to reduce the risk of cancer. Diallyl disulfide (DADS), a major garlic derivative, has exhibited potential role in cancer therapy. The study is aimed to evaluate the prophylactic effect of DADS in chemically induced mouse skin carcinogenesis and investigate the molecular targets mediated by ...

Epidemiologic studies show an inverse correlation between garlic consumption and progression of cardiovascular disease. However, the molecular basis for the beneficial effect of garlic on the heart is not known. Therefore, the objective of the present study was to (1) investigate the effect of raw garlic on isoproterenol (Iso) induced cardiac hypertrophy (2) find the active metabolites of garli...

Garlic (Allium sativum) has been used for centuries as a prophylactic and therapeutic medicinal agent. Importantly, garlic has been suggested to have both cancer-preventive potential as well as significant enhancing effects on the immune system. While these observations are supported experimentally both in vitro and in vivo, the impact of garlic in assisting the immune system in the prevention ...

Control of the skin parasitic ciliate Ichthyophthirius multifiliis is currently based on laborious chemical and mechanical approaches, thus advocating for alternative control measures. Here, we show that early development trophonts (feeding stage residing in epidermis) Rainbow Trout Oncorhynchus mykiss epidermis was inhibited at 5 d postinfection after administration feed additives, including g...

Hyperglycemia in the diabetic state increases oxidative stress and antioxidant therapy can be strongly correlated with decreased risks for diabetic complications. The purpose of this study is to determine antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes. The antioxidant activity of garlic and aged black garlic was measured as the activity in scavenging free ...