AIM The objective of this study was to estimate the effect of orlistat alone and in combination with Garcinia cambogia on visceral adiposity index (VAI) in obese patients. PATIENTS AND METHODS A total of 99 obese male patients were recruited with aged range between 37 and 46 years. They were randomized into three equal groups, first group treated with orlistat 120 mg/day, second group treated...

Five new triterpenes, one 17,14-friedolanostane (garcihombronane F, 1), three 17,13-friedolanostanes (garcihombronanes G-I, 2-4), and one lanostane (garcihombronane J, 5), were isolated from the leaves of Garcinia hombroniana together with nine known compounds including five triterpenes, two ionone-derived glycosides, and two flavonoid glucosides. Their structures were identified by analysis of...

In this dataset, we distinguish 15 accessions of Garcinia mangostana from Peninsular Malaysia using Fourier transform-infrared spectroscopy coupled with chemometric analysis. We found that the position and intensity of characteristic peaks at 3600-3100 cm(-) (1) in IR spectra allowed discrimination of G. mangostana from different locations. Further principal component analysis (PCA) of all the ...

Hydroxycitric acid (HCA) is a major acid component of the tropical plants Garcinia cambogia and Hibiscus subdariffa. (2S,3S)-HCA from G. cambogia was shown to be a potent inhibitor of ATP citrate lyase (EC4.1.3.8), which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA. (2S,3R)-HCA from H. subdariffa inhibits alpha-amylase and alpha-glucosidase, leading to red...

Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques

Garcinia has some 260 species and is often regarded as a genus with a difficult taxonomy. No recent treatment is available for the botanically rich Lower Guinea phytogeographical region. This study aims at partly filling this gap. First, several taxonomic problems are solved. Garcinia chromocarpa is reduced to a variety of Garcinia quadrifaria. Garcinia gnetoides and Garcinia granulata are both...

Garcinia mangostana L. (Mangosteen), of the family Clusiaceae, is one of the economically important tropical fruits in Indonesia. In the present study, we performed de novo transcriptomic analysis of Garcinia mangostana L. through RNA-Seq technology. We obtained the raw data from 12 libraries through Ion Proton System. Clean reads of 191,735,809 were obtained from 307,634,890 raw reads. The raw...

Garcinia cambogia (G.cambogia) is a herbal dietary supplement for managing obesity. Several adverse effects of G.cambogia have been reported including serotonin syndrome and mania. We report patient with refractory status epilepticus after taking G.cambogia. A 24-year-old woman was admitted continuing seizures. Based on electroencephalography neuroimaging findings, she diagnosed as attributed t...

A new species, Garcinia hopii H.Toyama & V.S.Dang is described from Bidoup Nui Ba National Park, southern Vietnam. This species is similar to Garcinia hendersoniana Whitmore but differs from that species in having larger leaves, clustered pistillate flowers, a greater number of sterile anthers and a larger stigma of young fruits. A description, preliminary conservation assessment, illustration,...

A xanthone, 1,3,6,7-tetrahydroxy-xanthone (compound (1)) had been isolated from Garcinia benthami Pierre. The isolation was conducted through the chromatography technique and spectroscopy methods by spectroscophyc: mass spectrometry (LC-MS), infra red (IR), UV, 1H-NMR, 13C-NMR (1D and 2D-NMR). Antioxidant activity test by using DPPH (1,1diphenyl-2-picrylhydrazyl) method from the isolated compou...