BACKGROUND AND OBJECTIVES Pseudomonas aeruginosa is a Gram-negative, aerobic bacterium found in water and soil. It is a normal flora in skin and gastrointestinal tract of human beings. P. aeruginosa as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibiotics. The aim of this study was to identify th...

Dormancy and germination requirements were investigated in seeds of Ferula gummosa Boiss (Apiaceae) and Teucrium polium L. (Labiatae). Seeds of both species were subjected to different treatments including various levels of GA3, HNO3, H2SO4, chilling and soaking with water at different temperatures. Germination of both species increased at higher concentrations of GA3. In the case of F. gummosa...

Objective: Cervical cancer is the second most common type of cancer among women, worldwide; and for treatment of this type of cancer radiotherapy is commonly used. Ferula gummosa Boiss(“Barije” in Persian, from the family Apiaceae), (F. gummosa), is an extremely precious medicinal plant which naturally grows throughout the Mediterranean and Central Asia and is a native plant in Iran. The presen...

Ferula asafoetida Linn. is a main source of asafoetida, a strong, tenacious and sulfurous odor, and oleo-gum resin of medicinal and nutritional importance. Asafoetida has been consumed as a spice and a folk medicine for centuries. Recent studies have shown several promising activities particularly relaxant, neuroprotective, memory enhancing, digestive enzyme, antioxidant, antispasmodic, hypoten...

Methanolic extracts of diff erent parts of fi ve medicinal plants, Ferula assafoetida L. resin, Grewia asiatica L. leaves, Ipomoea hederacea Jacq. seeds, Lepidium sativum L. seeds and Terminalia chebula Retz. fruits were tested in vitro for their cytotoxic, phytotoxic, insecticidal, nematicidal and anthelmintic activities. Ipomoea hederacea showed very signifi cant phytotoxic and cytotoxic acti...

Seven new sesquiterpene lactone glycosides (1-7) were isolated from the H2O-soluble fraction from the MeOH extract of the roots of Ferula varia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of compounds 1 and 2 were determined by modified Mosher's method.

ferula gummosa boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. there are also several reports on antioxidant effects of these compounds. the aim of this study was to investigate the effect of daily administration of f. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. twenty four wistar rats were randomly divided...