نتایج جستجو برای: g17

تعداد نتایج: 211  

Journal: :The Journal of clinical investigation 1986
S Pauwels H Desmond R Dimaline G J Dockray

Recent studies on the gene sequence encoding the human pyloric antral hormone, gastrin, indicate a precursor of 101 residues. We have now raised antibodies to a synthetic analogue corresponding to (Tyr)-human progastrin COOH-terminal pentapeptide. The antibodies could be used in radioimmunoassay to measure this peptide, but they did not react with corresponding fragments of procholecystokinin, ...

Journal: :The Journal of clinical investigation 1987
H J Lenz T Struck H Greten M A Koss V E Eysselein J H Walsh J I Isenberg

We studied acid secretory responses to exogenous pentagastrin and to exogenous and endogenous gastrin in 12 stable cirrhotic subjects with portacaval shunt, 12 unshunted cirrhotics, and 12 normal subjects. Basal and stimulated serum gastrin concentrations as well as basal and maximum acid outputs were similar in the three groups. At low doses of either exogenous pentagastrin or gastrin-17 (G17)...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2005
P D Ottewell A Varro G J Dockray C M Kirton A J M Watson T C Wang R Dimaline D M Pritchard

Transgenic mice (hGAS) that overexpress human progastrin are more susceptible than wild-type mice (FVB/N) to the induction of colonic aberrant crypt foci (ACF) and adenomas by the chemical carcinogen azoxymethane. We have previously shown significantly increased levels of colonic mitosis in hGAS compared with FVB/N mice after gamma-radiation. To investigate whether the effects of progastrin obs...

Journal: :Journal of Clinical Medicine 2023

Background: Autoimmune gastritis (AIG), characterized with the presence of anti-parietal-cell antibodies (APCA), is a risk factor for gastric cancer. However, AIG may go underdiagnosed, especially in case H. pylori infection and precancerous lesions (GPL), due to ambiguous pathology delayed symptom onset. Aim: Investigate prevalence characteristics GPL patients. Methods: Prevalence was determin...

2014
Adrian G. McNicholl Montserrat Forné Jesus Barrio Cristobal De la Coba Begoña González Robin Rivera Maria Esteve Fernando Fernandez-Bañares Beatriz Madrigal Beatriz Gras-Miralles Angeles Perez-Aisa Jose M. Viver-Pi-Sunyer Felipe Bory Merce Rosinach Carmen Loras Carlos Esteban Santos Santolaria Fernando Gomollon Julio Valle Javier P. Gisbert

BACKGROUND It has been suggested that GastroPanel might be a useful tool for the diagnosis of chronic atrophic gastritis (CAG) measuring four biomarkers in blood: basal gastrin-17 (G17), pepsinogen I and II (PGI and PGII), and Helicobacter pylori antibodies. AIM To determine the accuracy of GastroPanel for the diagnosis of CAG. METHODS This was a prospective, blinded, multicenter study that...

Journal: :Cancer research 2006
Philip A Clarke Jacqueline H Dickson Joseph C Harris Anna Grabowska Susan A Watson

This study examined whether gastrin modulates endothelial cell activity via heparin-binding epidermal growth factor-like growth factor (HB-EGF) expression. Human umbilical vascular endothelial cells (HUVEC) were assessed for tubule formation in the presence of amidated gastrin-17 (G17) and glycine-extended gastrin-17 (GlyG17) peptides. HB-EGF gene and protein expressions were measured by quanti...

2016
Yuji Fujii Hiromichi Mitake Daigo Yamada Makoto Nagai Kota Okadera Naoto Ito Kazuma Okada Kento Nakagawa Tetsuya Mizutani Makoto Sugiyama

To obtain complete genome sequences of turkey rotavirus A strains Ty-1 and Ty-3, we sequenced the gene segments that had not been decoded previously. The genotype constellations of the respective strains were determined to be G17-P[38]-I4-R4-C4-M4-A16-N4-T4-E4-H4 and G7-P[35]-I4-R4-C4-M4-A16-N4-T4-E11-H14. Notably, their VP4 and NSP5 genes were classified into novel genotypes.

Journal: :Fermentation 2023

Astaxanthin is increasingly attracting commercial interest for its application in the nutraceutical and pharmaceutical industries. This study aimed to produce astaxanthin from molasses with our newly mutated strain of Rhodosporidium toruloides G17 evaluate biological activities produced astaxanthin. To maximize yield, response surface methodology was used so as optimize culture conditions. A ma...

Journal: :Agrosystems, geosciences & environment 2023

Abstract A total of 24 oat genotypes were evaluated across 9 environments using a randomized complete block design with 3 replications. The combined analysis variance indicated that grain yield was significantly affected by genotype, environment, and genotype environment interaction (GEI). environment's main effect explained 44.62% the variation, whereas GEI captured 28.84% 26.54%, respectively...

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