In Drosophila, distinct mechanisms orient asymmetric cell division along the apical-basal axis in neuroblasts and along the anterior-posterior axis in sensory organ precursor (SOP) cells. Here, we show that heterotrimeric G proteins are essential for asymmetric cell division in both cell types. The G protein subunit G(alpha)i localizes apically in neuroblasts and anteriorly in SOP cells before ...

Printing with custom inks is of interest both for artistic purposes and for printing security documents such as banknotes. However, in order to create designs with only a few custom inks, a general purpose high-quality gamut reduction technique is needed. Most existing gamut mapping techniques map an input gamut such as the gamut of a CRT display into the gamut of an output device such as a CMY...

The fractional reaction diffusion equation ∂tu+Au = g(u) is discussed, where A is a fractional differential operator on R of order α ∈ (0, 2), the C function g vanishes at ζ = 0 and ζ = 1 and either g ≥ 0 on (0, 1) or g < 0 near ζ = 0. In the case of non-negative g, it is shown that solutions with initial support on the positive half axis spread into the left half axis with unbounded speed if g...

The 1.25 Å resolution H32:R crystal structure of a 20 nt ribonucleotide that binds to the TREX-2 complex with high affinity shows a double-stranded RNA duplex arranged along a crystallographic 31 axis in which the antiparallel chains overlap by 18 nucleotides and are related by a crystallographic twofold axis. The duplex shows C-A, U-U and C-C noncanonical base pairings together with canonical ...

We characterize two types of bar-visibility graphs on the Mobius band (abbreviated "BVGMs"), in which vertices correspond to intervals that are parallel or orthogonal to the axis of the band, depen­ ding on type, and in which adjacency corresponds to orthogonal visibility of intervals. BVGMs with intervals orthogonal to the axis are shown to be equivalent to the "polar visibility graphs" studie...

This paper reports a microfabricated piezoelectric MEMS inertial energy harvester that can scavenge high-frequency mechanical vibrations in all three dimensions with an active inner volume of only 55 mm. The device can generate 0.1 to 10.5 μW from out-of-plane vibrations (365-465 Hz), and 0.1 to 3.2 μW from in-plane vibrations (680-930 Hz) at 0.5 g acceleration input. The reported harvester is ...

Introduction: Different mechanisms are involved in stress induced analgesia (SIA) and hyperalgesia (SIH). Repeated stress induces development of tolerance to SIA. The role of HPA axis and Gs signaling pathway in these effects are investigated in the current study. Methods: Forced swim stress (5 min/day) in water (20±1 ºC) was employed to adult male Wistar rats (200-250 g). The nociceptive t...

Transthoracic Echocardiography : The transthoracic study was done by using Philips HD 11 XE Machine with a multifrequency S4-2 transducer. The echocardiographic examination included use of various views parasternal long axis view, parasternal short axis view, apical four chamber view, apical two chamber view and sub costal view if necessary. Thrombus, vegetation and tumor were d i a g n o s e d...