BACKGROUND Fungal keratitis is basically treated by medications. Several cases of fungal keratitis were reported around the world to have been treated successfully by corneal graft--penetrating keratoplasty (PKP). Studies have shown that PKP is a useful treatment, preserves eye globe integrity, and rehabilitates vision in patients with advanced fungal keratitis. AIM To study the use of penetr...

Keratitis is an inflammation of the cornea (the clear, front part of the eye) and is often caused by bacteria, viruses, amoeba, fungi. There are two types of keratitis infectious ulcerative keratitis (IUK), caused by infectious pathogens and noninfectious ulcerative keratitis (NIUK), which has a clinical presentation similar to that of IUK but no known infectious cause and is a diverse disease ...

purpose: to determine the sensitivity and specificity of confocal scan in the diagnosis of fungal and acanthamoeba keratitis based on the results of corneal and/or contact lens case smear and culture. method: confocal scan and corneal and/or contact lens case smear and culture were performed in all patients with a clinical diagnosis of infectious keratitis who were referred to labbafinejad medi...

Penetrating keratoplasty carries an infectious risk. Its requirement for topical corticosteroid therapy facilitates fungal growth with resulting keratitis. Although progression of fungal keratitis to intraocular infection is uncommon, endophthalmitis resulting from keratitis usually has a poor visual prognosis. Fungal infection under these circumstances remains a diagnostic and therapeutic chal...

PURPOSE Introducing a simple image grading system to support the interpretation of in vivo confocal microscopy (IVCM) images in filamentous fungal keratitis. SETTING Clinical and confocal studies took place at the Department of Ophthalmology, Aarhus University Hospital, Denmark. Histopathological analysis was performed at the Eye Pathology Institute, Department of Neuroscience and Pharmacolog...

BACKGROUND & OBJECTIVE Infective keratitis is rare in the absence of predisposing factors. The pattern of risk factors predisposing to infective keratitis varies with geographical regions and also influences the type of infection that occurs. The present study was aimed to identify the specific risk factors that predispose the infective keratitis (non viral) and to determine the association bet...

PURPOSE Neutrophils release neutrophil extracellular traps (NETs) when defending against invading microorganisms. We investigated the existence of NETs in fungal keratitis. METHODS Fourteen patients with unilateral fungal keratitis were included. Detailed information about each patient was recorded, including (1) patient history (onset of symptoms and previous therapy), (2) ocular examination...

BACKGROUND Mycotic keratitis is an important cause of corneal blindness world over including India. Geographical location and climate are known to influence the profile of fungal diseases. While there are several reports on mycotic keratitis from southern India, comprehensive clinico-microbiological reports from eastern India are few. The reported prevalence of mycotic keratitis are 36.7%,36.3%...

PURPOSE OF REVIEW Throughout the world, fungal keratitis is a leading cause of ocular morbidity. The purpose of this review is to discuss the recently published literature in relation to the epidemiology, etiology, diagnosis, and therapy of fungal keratitis. RECENT FINDINGS Globally, the incidence of keratomycoses and systemic mycoses is rising. Current therapies are often ineffective. Ongoin...

microbial corneal diseases are a serious ocular infection and the major cause of ocular morbidity and blindness in the world. the outcomes of fungal keratitis are unfavorable due to the protracted course of the condition and the diversity of respective clinical presentations. trauma, contact lens wear, foreign material, and prior corneal surgery, may make the most background for permitting inva...