PURPOSE To analyze high-resolution color photographs of the mouse fundus. METHODS A contact fundus camera based on topical endoscopy fundus imaging (TEFI) was built. Fundus photographs of C57 and Balb/c mice obtained by TEFI were qualitatively analyzed. RESULTS High-resolution digital imaging of the fundus, including the ciliary body, was routinely obtained. The reflectance and contrast of ...

The proficiency of nonophthalmologists with direct ophthalmoscopy is poor, which has prompted a search for alternative technologies to examine the ocular fundus. Although ocular fundus photography has existed for decades, its use has been traditionally restricted to ophthalmology clinical care settings and textbooks. Recent research has shown a role for nonmydriatic fundus photography in nonoph...

To report a case of bilateral isolated foveal hypoplasia in which multimodal imaging was used to confirm the diagnosis. Fundus autofluorescence imaging, optical coherence tomography (OCT), and fundus fluorescein angiography were used to describe the typical findings of a patient with isolated foveal hypoplasia. Spectral domain OCT showed absence of foveal depression and persistent inner retinal...

PURPOSE To investigate the feasibility and to identify sources of experimental variability of quantitative and qualitative fundus autofluorescence (AF) assessment in mice. METHODS Blue (488 nm) and near-infrared (790 nm) fundus AF imaging was performed in various mouse strains and disease models (129S2, C57Bl/6, Abca4(-/-), C3H-Pde6b(rd1/rd1), Rho(-/-), and BALB/c mice) using a commercially a...

localizing the optic disc (od) in retinal fundus images is of critical importance, since it is very similar to hard exudates (found in pathology) in color and brightness. because of the importance of od localization in clinical applications, many techniques have been developed. in this paper, we present the results obtained from two methods, correlation and least square, to approximate the opti...

Introduction: Age-related macular degeneration (AMD) is one of the major causes of visual loss among the elderly. It causes degeneration of cells in the macula. Early diagnosis can be helpful in preventing blindness. Drusen are the initial symptoms of AMD. Since drusen have a wide variety, locating them in screening images is difficult and time-consuming. An automated digital fundus photography...

A technique based on the method of differential fundus reflectometry is used to assess the availability of rhodopsin in the eye. A defined part of the dark adapted fundus is bleached by a short intense flash of light. The fundus is subsequently photographed in order to record the flux reflected from the bleached area, the optogram, and the surrounding unbleached region. This procedure requires ...