Functional brain mapping with magnetic resonance imaging (MRI) is a rapidly growing field that has emerged in only the past several years. Functional MRI (fMRI) is the use of MRI equipment to detect regional changes cerebral metabolism or in blood flow, volume or oxygenation in response to task activation. The most popular technique utilizes blood oxygenation level dependent (BOLD) contrast, wh...

Functional MRI (fMRI) was used to examine gender effects on brain activation during a language comprehension task. A large number of subjects (50 women and 50 men) was studied to maximize the statistical power to detect subtle differences between the sexes. To estimate the specificity of findings related to sex differences, parallel analyses were performed on two groups of randomly assigned sub...

A new information-theoretic approach is presented for analyzing fMRI data to calculate the brain activation map. The method is based on a formulation of the mutual information between two waveforms{ the fMRI temporal response of a voxel and the experimental protocol timeline. Scores based on mutual information are generated for all voxels and then used to compute the activation map of an experi...

Kim fMRI Methods 2 1. Introduction The idea that regional cerebral blood flow (CBF) could reflect neuronal activity began with experiments of Roy and Sherrington at 1890 (1). This concept is the basis for all hemodynamic-based brain imaging techniques being used today. The focal increase in CBF can be considered to directly relate to neuronal activity because the glucose metabolism and CBF chan...

Most brain imaging researchers would agree with the assertion that functional MRI (fMRI) is progressing. Since fMRI began in 1991, the number of people, papers, and abstracts related to fMRI has been increasing; the technology and methodology has shown advances in robustness and sophistication; the physiology of the signal is better understood; and, even though it hasn't yet made significant he...

introduction a discoid medial meniscus is a rare pathology of the knee joint, and is even rarer when it presents bilaterally with clinical symptoms. case presentation we present the case of a 38-year-old female with symptomatic bilateral discoid medial meniscus. magnetic resonance imaging (mri) showed complete discoid meniscus in one knee and incomplete, on the other side. the mri findings were...