To allow chromosome segregation, topoisomerase II (topo II) must resolve sister chromatid intertwines (SCI) formed during deoxynucleic acid (DNA) replication. How this process extends to the full genome is not well understood. In budding yeast, the unique structure of the ribosomal DNA (rDNA) array is thought to cause late SCI resolution of this genomic region during anaphase. In this paper, we...

Abstract. The aim of the work was to study effect growth regulator “Epin-Ekstra” on yield and quality indicators potato tubers Nevskiy variety by results field experiments. Methods. studies set objectives were carried out conditions in foothill zone Republic North Ossetia-Alania experimental section Caucasus Scientific Research Institute Mountain Foothill Agriculture – branch Federal Center “Vl...

The Drosophila neuromuscular junction (NMJ) is capable of rapidly budding new presynaptic varicosities over the course of minutes in response to elevated neuronal activity. Using live imaging of synaptic growth, we characterized this dynamic process and demonstrated that rapid bouton budding requires retrograde bone morphogenic protein (BMP) signaling and local alteration in the presynaptic act...

Removal of potassium from Hydra culture medium produces a decrease in intracellular potassium and a parallel decrease in asexual growth rate. Rubidium and caesium are ineffective as substitutes for potassium in the maintenance of growth rate. Increases in intracellular potassium parallel increases in growth rate up to a level somewhat below the normal steady-state level of intracellular potassi...

Cellular DNA topoisomerases (topo I and topo II) are highly conserved enzymes that regulate the topology of DNA during normal genome transactions, such as DNA transcription and replication. In budding yeast, topo I is dispensable whereas topo II is essential, suggesting fundamental and exclusive roles for topo II, which might include the functions of the topo IIa and topo IIb isoforms found in ...

The articles [17], [16], [21], [15], [3], [18], [25], [1], [9], [10], [4], [8], [2], [19], [24], [14], [20], [13], [12], [11], [23], [5], [7], and [22] provide the terminology and notation for this paper. Let n be a natural number and let x, y be finite sequences. The functor n-BitSubtracterStr(x, y) yields an unsplit non void strict non empty many sorted signature with arity held in gates and ...

In this article we continue the investigations from [5] of verification of a design of adder circuit. We define it as a combination of 1-bit adders using schemes from [6]. n-bit adder circuit has the following structure 1st bit adder x 1 y 1 x 2 y 2 r 1 r 2 2nd bit adder nth bit adder x n y n r n As the main result we prove the stability of the circuit. Further works will consist of the proof o...

ObjectiveTo report a successful case of ovarian hyperstimulation and oocyte cryopreservation in transgender male adolescent after suppression with gonadotropin-releasing hormone (GnRH) agonist while using the aromatase inhibitor letrozole to maintain low serum estradiol.DesignCase report.SettingDivision Reproductive Endocrinology Infertility, Washington University St. Louis School Medicine, St ...

PURPOSE Gastric carcinoma (GC) is a highly aggressive cancer and one of the leading causes of cancer-related deaths worldwide. Histopathological evaluation pertaining to invasiveness is likely to provide additional information in relation to patient outcome. In this study, we aimed to evaluate the prognostic significance of tumor budding and single cell invasion in gastric adenocarcinoma. MAT...