Twelve apparently healthy and recently parturiated Murrah buffaloes, vaccinated with Foot-and-mouth disease (FMD) + Haemorrhagic septicaemia (HS) combined vaccine at an organized farm along their newborn calves were inducted for detection of antibodies in serum colostrum against FMD virus (FMDV) serotypes O, A Asia-1, Pasteurella multocida using enzyme linked immunosorbent assay. The born to da...

Antigen and vaccine banks are stocks of immunogenic materials ready to be formulated into vaccines (bulk antigens) or ready to use (vaccines) in case of need by one or more of the parties of the bank. These stocks were primarily developed by foot and mouth disease [FMD] free European countries to control unexpected severe FMD episodes after the cessation of routine vaccination in the 1990s. For...

The Global Foot-and-mouth disease (FMD) Research Alliance periodically reviews the state of FMD research to assess progress and to identify new priorities. In this supplement we provide an update of global FMD research, comprising (i) this overview paper, which includes background information with key findings, and papers covering (ii) epidemiology, wildlife and economics, (iii) vaccines, (iv) ...

Aim: The present work was established in order to investigate the effect of ultra-corn administration on the immune response of vaccinated calves with FMD bivalent oil vaccine. Material and Methods: Forty calves; at a private farm in EL-Fayoum Governorate (Locality A); were divided into 4 groups nd rd th where the first group was vaccinated with the locally produced FMD bivalent oil vaccine alo...

foot-and-mouth disease is an important viral disease of cloven-hoofed animals. inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. the choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. montanide isa 61 vg is a new ready-to-use mineral oil-based adjuvant developed by seppic inc....

Since the signing in 1987 of the Hemispheric Plan for the Eradication of Foot-and-Mouth Disease (PHEFA) by the countries of South America, clinical cases of foot and mouth disease (FMD) have decreased significantly throughout the continent. During the early 1990s, national laboratories diagnosed an average of 766 cases per year in South America. By the late 1990s, this continent-wide average ha...

There are seven antigenically distinct serotypes of foot-and-mouth disease virus (FMDV), each of which has intratypic variants. In the present study, we have developed methods to efficiently generate promising vaccines against seven serotypes or subtypes. The capsid-encoding gene (P1) of the vaccine strain O1/Manisa/Turkey/69 was replaced with the amplified or synthetic genes from the O, A, Asi...

Caron L., Brum M.C.S., Moraes M.P., Golde W.T., Arns C.W. & Grubman M.J. 2005. [Granulocyte-macrophage colony-stimulating factor does not increase the potency or efficacy of a foot-and-mouth disease virus subunit vaccine.] Pesquisa Veterinária Brasileira 25(3):150-158. USDA, ARS, PIADC-FMD Research Unit, PO.Box 848, Greenport, NY 11944 0848, USA. E-mail: [email protected] Foot-and-mou...

Foot and mouth disease (FMD) is a highly infectious and economically devastating disease of livestock. Although vaccines, available since the early 1900s, have been instrumental in eradicating FMD from parts of the world, the disease still affects millions of animals around the globe and remains the main sanitary barrier to the commerce of animals and animal products. Currently available inacti...

Foot-and-mouth disease (FMD) is one of the most serious threats to the livestock industry. Despite the availability of a vaccine, recent outbreaks in disease-free countries have demonstrated that development of novel FMD control strategies is imperative. Here we report the identification and characterization of bovine (bo) interferon lambda 3 (IFN-λ3), a member of the type III IFN family. Expre...