Spray drying is gaining traction in the pharmaceutical industry as one of processing methods choice for manufacture solid dosage forms intended pulmonary, oral, and parenteral delivery. This process particularly advantageous because its ability to produce engineered particles with improved efficacy stability by combining active ingredients or biologics appropriate excipients. Moreover, due high...

background : the main objective of this study was to design, formulate and evaluate the physicochemical properties of 500 mg acetaminophen effervescent tablets, in order to accelerate its analgesic and antipyretic effects in patients with pill swallowing problems. methods : formulations with 500 mg of acetaminophen were prepared with effervescent bases including tartaric acid, citric acid, sodi...

background: orally disintegrating tablets (odts) are a modern form of tablets that when placed in the oral cavity, disperses rapidly. these tablets have advantages, particularly good applications for children and old patients who have a complication in chewing or swallowing solid dosage forms. the aim of this study was to design, formulate, and evaluate the physicochemical properties of 5 mg mo...

A novel mathematical model has been developed to aid the formulation of emulsion explosives. This mathematical model calculated heat of explosion, oxygen balance and raw material cost as a function of explosive ingredients, and the solution of the mathematical model was obtained by a MS Excel program. The effects of the different content of NH4NO3, NaNO3, H2O, and span-80 and composite fuel oil...

Waterborne Epoxy based coatings were prepared by using a water-borne epoxy resin and a suitable hardener. The formulation and optimization procedure were carried out on the bases of experimental designs by the mixture design technique in which the important paint properties are modeled by using special cubic model. The corrosion behavior of these coatings was investigated using electrochemical ...

Abstract Levetiracetam as an Anti-epileptic drug with exclusive mechanism of action is accepted by the USA Food and Drug Administration as an adjunctive therapy in treating epilepsy in young adults. The purpose of this project is the design and formulation of prolonged release of levetiracetam using two types of retarding agent such as Hydroxyl Propyl Methylcellulose (HPMC K4...

the aim of this study was to investigate the processing methods of sorghum grain and diet formulation on performance and nutrients digestibility in broilers. three hundred and twenty chicks at eight day of age were allotted into eight groups of four replicate with ten chicks per replicate. this research was conducted as completely randomized design arranged in a 2 × 2 × 2 factorial experiment u...

Chewable ferrous fumarate tablet is the best iron dosage form for children due to better compliance and lower teeth staining compared to the oral drop. Because of the different desirable properties of chewable tablets and the opposing effects of fillers on them, the mathematical experimental design was used as the formulation approach. Different series of formulations based on single filler (La...