Specific and sensitive in vitro bioassays suitable for measurement of follicle-stimulating hormone (FSH) in small quantities of serum and urine have recently been validated. Comparisons of bioassay (B-FSH) potencies with immunoassay (I-FSH) estimates and chromatofocusing patterns have facilitated new discoveries regarding the regulation of FSH biosynthesis, storage, secretion, serum concentrati...

A highly purified follicle-stimulating hormone from human pituitary glands has been prepared by ammonium sulfate and ethanol fractionation, gel filtration on Sephadex G-100, ion exchange chromatography on carboxymethyl cellulose, zone electrophoresis on cellulose columns, and preparative continuous flow polyacrylamide gel electrophoresis. The final product has shown lO,OOO-fold purification ove...

A highly purified follicle-stimulating hormone from human pituitary glands has been prepared by ammonium sulfate and ethanol fractionation, gel filtration on Sephadex G-100, ion exchange chromatography on carboxymethyl cellulose, zone electrophoresis on cellulose columns, and preparative continuous flow polyacrylamide gel electrophoresis. The final product has shown lO,OOO-fold purification ove...

Background and Objective: As infertility is rapidly becoming a major medical problems among Sudanese females, that has an impact on ovulation and menstruation and other complications, the aim of our present study to investigate the concentration and evaluate potential role of luteinizing hormone, follicle stimulating hormone and esteradiol in Sudanese infertile females, that may help and facili...

Background: Infertility is defined as the inability to conceive after one two years of unprotected intercourse. It types: primary infertility and secondary 5On basis etiopathology divided into five groups: unexplained (28%), male factor (24%), ovarian dysfunction (21%), tubal (14%) others (13%). Luteinizing hormone (LH) follicle-stimulating (FSH) are integral parts neural endocrine interchange ...

The potential influence of hormonal imbalance on the development of slipped capital femoral epiphysis was assessed through a prospective clinical study. The serum levels of T3, T4, thyroid-stimulating hormone, testosterone, estradiol, dehydroepiandrosterone-sulfate, follicle-stimulating hormone, luteinizing hormone, human growth hormone, adrenal cortex hormone and cortisol were evaluated in sev...

OBJECTIVE This study evaluated the use of Corifollitropin alfa in patients with previous poor response to recombinant follicle stimulating hormone in long-term protocols using gonadotropin-releasing hormone. METHODS Twenty-seven poor responders to previous treatment with the long term protocol using the recombinant follicle stimulating hormone (Group 1) were selected and then submitted to a s...

Treatment of immature mice with both follicle-stimulating hormone and human chorionic gonadotrophin in vivo resulted in large increases in the specific activities of ovarian alkaline phosphatase and alkaline nucleotidase. The specific activities of other ovarian enzymes studied were not altered by gonadotrophin treatment. A simultaneous change in the Michaelis constant of ovarian alkaline phosp...