The development of transgenic reporter mice and advances in in vivo optical imaging have created unique opportunities to assess and analyze biological responses to thermal therapy directly in living tissues. Reporter mice incorporating the regulatory regions from the genes encoding the 70 kDa heat-shock proteins (Hsp70) and firefly luciferase (luc) as reporter genes can be used to non-invasivel...

Abstract Short nanofibers have been of interest in preparing 3D porous structures, aerosol filters, and nanocomposites. These materials require nanofiber retrieval application short form with simultaneous control over aspect ratio. Electrospinning, conventionally, offers minimal yield as nonwoven mat is the default configuration collected sample. High surface area to volume ratio nanofiber, how...

Background: Bipolar mood disorder type 1 is one of the most serious psychiatric disorders. We aimed to assess the efficacy of a short-term family–focused treatment for patients with bipolar mood disorder type 1 in a one-year follow-up period. Methods: Sixty patients with bipolar mood disorder and acute mania episodes who referred to Ibn-e-Sina Psychiatric Hospital in Mashhad were recruited. Hal...

Laser-enhanced cavitation during high intensity focused ultrasound (HIFU) was studied in vivo using a small animal model. Laser light was employed to illuminate the sample concurrently with HIFU radiation. The resulting cavitation was detected with a passive cavitation detector. The in vivo measurements were made under different combinations of HIFU treatment depths, laser wavelengths, and HIFU...

According to Paracelsus (1493-1541) everything from this planet is poison, only the dose makes the poison to be harmless. Even the essential elements for life support are toxic for all organisms in high amounts. Mercury, cadmium, metalloid arsenic and lead were responsible for poisoning and death of many humans and life forms from this planet for centuries. Cadmium forms different compounds tha...