Renal replacement therapy can be applied either in an intermittent fashion or in a continuous fashion in severe acute kidney injury. To date, no modality has been shown to consistently improve patient survival. In the study recently reported by Sun and colleagues, continuous application of renal replacement therapy was associated with improved renal recovery, defined by lower risk of long-term ...

neonatal hypoglycemia is common and its prompt ‎management is important to reduce neurological sequelae. to determine the effect of two different glucose concentrations of intravenous (iv) fluid ‎therapy in the incidence of hypoglycemia in sick premature infants, 200 preterm infants ‎weighing 1500-2500 g were selected and randomly assigned into two groups. ‎group 1 received 10% dextrose in wate...

conclusions according to our results, the infusion of one liter normal saline will cause a statistically significant decrease only in bd, after one hour, in patients with moderate to severe iss. the changes in sbp, pr, cvp and also ph, hco3 and hb were not statistically remarkable. background the management of trauma patients is often difficult. the american college of surgeons suggests using a...

BACKGROUND Although associated with severe clinical complications, phosphate remains a neglected ion. Additionally, phosphate balance during continuous renal replacement therapy (CRRT) is complex and multifunctional. The present retrospective study investigated the effects of phosphate-containing CRRT fluid on phosphate homeostasis. METHODS We retrospectively analysed 112 patients treated wit...

OBJECTIVE Identify prognostic factors related to mortality and non-recovery of renal function. METHODS A prospective single-center study was conducted at the intensive care medicine department of a university hospital between 2012 and 2015. Patients with acute kidney injury receiving continuous renal replacement therapy were included in the study. Clinical and analytical parameters were colle...

background: nephrotoxicity is one of the major side-effects of cisplatin that has been seen in about 20% of treated patients. the aim of this study was to assess the effectiveness of a forced hydration protocol comprised of isotonic saline, potassium chloride (kcl) and magnesium sulfate (mgso4) on prevention of cisplatin nephrotoxicity. methods: this cross sectional prospective study was perfor...

Although most women with type 1 diabetes experience the normal transition to menopause, there is little information about the impact of hormone replacement therapy on their glycemic profiles. A 54-year-old postmenopausal woman with fulminant type 1 diabetes was admitted to our hospital due to diabetic ketoacidosis. She was treated with fluid replacement and a continuous insulin infusion. Therea...

In patients with acute kidney injury and concomitant severe hyponatraemia or hypernatraemia, rapid correction of the serum Na+ concentration needs to be avoided. The present paper outlines the principles of how to adjust the Na+ concentration in the replacement fluid during continuous renal replacement therapy to prevent rapid changes of the serum Na+ concentration.

OBJECTIVE Continuous renal replacement therapy (CRRT) is a continuous process of bedside blood purification which is widely used in the treatment of acute kidney injury (AKI) and for fluid management. However, since AKI and fluid overload are often found to be associated with hemodynamic abnormalities, determining the relationship between CRRT and hemodynamics remains a challenge in the treatme...

Perioperative fluid therapy is the subject of much controversy, and the results of the clinical trials investigating the effect of fluid therapy on outcome of surgery seem contradictory. The aim of this chapter is to review the evidence behind current standard fluid therapy, and to critically analyse the trials examining the effect of fluid therapy on outcome of surgery. The following conclusio...