L. Vu, B. Swartz, K. Head, M. Mandelkern, O. Nalcioglu, M-Y. Su Tu & Yuen Center for Functional Onco Imaging, University of California, Irvine, Irvine, CA, United States, Epilepsy Center, Hoag Hospital, Newport Beach, CA, United States, Department of Physics, University of California, Irvine, Irvine, CA, United States Purpose It has been known that patients with Juvenile Myoclonic Epilepsy (JME...

Facilitatory Neural Dynamics for Predictive Extrapolation. (August 2006) Heejin Lim, B.S., Keimyung University; M.S., Keimyung University Chair of Advisory Committee: Yoonsuck Choe Neural conduction delay is a serious issue for organisms that need to act in real time. Perceptual phenomena such as the flash-lag effect (FLE) suggest that the nervous system may have mechanisms to compensate for de...

A moving object is perceived to lie beyond a static object presented at the same time at the same retinal location (flash-lag effect or FLE). Some studies report that if the moving stimulus stops moving (flash-terminated condition or FTC) the instant the flash occurs, a FLE does not occur. Other studies, using different stimuli, report that the FLE does, in fact, occur in the FTC. The FTC is th...

In childhood frontal lobe epilepsy (FLE), cognitive impairment and educational underachievement are serious, well-known co-morbidities. The broad scale of affected cognitive domains suggests wide-spread network disturbances that not only involves, but also extends beyond the frontal lobe. In this study we have investigated whole brain connectional properties of children with FLE in relation to ...

AIM OF THE STUDY was to provide new data about the evolution of neuropsychological findings in patients with lesional frontal lobe epilepsy (FLE) operated on with lesion excision. PATIENTS AND METHODS Twelve patients with lesional FLE underwent full clinical examination including neurological, neuropsychological and developmental assessments, high-resolution magnetic resonance imaging (MRI), ...

Point-based rigid registration is the method of choice for aligning medical datasets in diagnostic and image-guided surgery systems. The most clinically relevant localization error measure is the Target Registration Error (TRE), which is the distance between the image-defined target and the corresponding target defined on another image or on the physical anatomy after registration. The TRE dire...

BACKGROUND When a moving stimulus and a briefly flashed static stimulus are physically aligned in space the static stimulus is perceived as lagging behind the moving stimulus. This vastly replicated phenomenon is known as the Flash-Lag Effect (FLE). For the first time we employed biological motion as the moving stimulus, which is important for two reasons. Firstly, biological motion is processe...

Several accounts put forth to explain the flash-lag effect (FLE) rely mainly on either spatial or temporal mechanisms. Here we investigated the relationship between these mechanisms by psychophysical and theoretical approaches. In a first experiment we assessed the magnitudes of the FLE and temporal-order judgments performed under identical visual stimulation. The results were interpreted by me...

A problem in the search for an efficient vaccine against dengue virus is the immunodominance of the fusion loop epitope (FLE), a segment of the envelope protein E that is buried at the interface of the E dimers coating mature viral particles. Anti-FLE antibodies are broadly cross-reactive but poorly neutralizing, displaying a strong infection enhancing potential. FLE exposure takes place via dy...

• Unlike temporal lobe epilepsy (TLE), the many semiologic features of frontal lobe epilepsy (FLE) are protean, and often epileptiform discharges or ictal patterns on EEG are not localized. • We highlight 2 lesser-known signs associated with FLE: 1. Ictal pouting, also known as the chapeau de gendarme sign, is an easily recognizable facial expression with its origins in the frontal lobe, seen e...