We report a case of fixed drug eruption caused by fluconazole. A local provocation with 10% fluconazole test in petrolatum applied at the site of a previous lesion of fixed drug eruption reproduced the eruption clinically and histopathologically.

BACKGROUND Nimesulide is a cyclooxygenase (COX) inhibitor with a high degree of selectivity to COX-2. It is a widely used and well tolerated nonsteroidal antiinflammatory drug that also has analgesic and antipyretic properties. The most frequently reported side effects concern the gastrointestinal tract. Pruritus and skin rash are the most common cutaneous adverse reactions. There are only eigh...

We report on a rare case of fluconazole induced fixed drug eruption in a 62-year old female patient. She was referred to our department for multiple erythematous itchy maculopatches on the face, neck, both upper arms, and trunk area, which had occurred over the previous 6 months. Her attending physician prescribed fluconazole for treatment of onychomycosis. Patch test and oral provocation were ...

Fixed drug eruption is a common adverse effect seen with various drugs notably antibiotics, antiepileptics and non-steroidal anti-inflammatory drugs. Herein we report a case of Sitagliptin induced fixed drug eruption in a 46 year old female who developed circumscribed, erythematous macules all over the body within one week of initiation of Sitagliptin. The lesions resolved with residual hyperpi...

INTRODUCTION Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However, this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report. CASE PRESENTATION A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

BACKGROUND The diagnosis of fixed 'drug' eruption is not difficult for dermatologists, but it is difficult to identify the causative agent when the patient denies ingestion of any drugs. There have been some reported cases of fixed 'food' eruption. CASE SUMMARY A 71-year-old woman experienced repeated erythema and tense bulla with a burning sensation and pruritus on the right ankle. The erupt...