background and objectives: fine needle aspiration cytology (fnac) is an established out- patient procedure used in primary diagnosis of palpable thyroid lesions. a modified technique fine needle capillary sampling (fncs) obviates the need of suction, is less painful, patient friendly and reported to overcome the problem of inadequate and bloody specimens. the aim of our study was to compare the...

PURPOSE Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used to analyze tumor sections and can determine tumor type, nodal involvement, and survival, and shows promise in predicting therapeutic response. Our purpose was to develop a method compatible with MALDI-TOF MS that allows selective analysis of cancer cells in mixed clinical samples su...

CONTEXT AND OBJECTIVE Fine-needle aspiration biopsy has been accepted worldwide for breast lesions. However, some questions remain, including the appropriateness of the puncture method. The objective of this work was to compare aspirates obtained by the auto-vacuum device and by the syringe pistol holder. DESIGN AND SETTING Randomized trial for validation of diagnostic method, at Hospital das...

conclusions the aspirates from the hypovascular and hypervascular sites of solid nodules are complementary and should be performed consecutively. results when only hypervascular site was used, adequate sampling was limited to 65% of the cases. when both sites were evaluated together, overall adequate sampling was 91%. adding a sample from the hypervascular site to hypovascular aspirate increase...